Sharma Gaurav K, Poulin Marie-France, Schaer Gary L
Department of Medicine, Division of Cardiology, Rush University Medical Center, Chicago, IL, United States.
Department of Medicine, Division of Cardiology, Rush University Medical Center, Chicago, IL, United States.
Cardiovasc Revasc Med. 2018 Dec;19(8S):50-52. doi: 10.1016/j.carrev.2017.05.011. Epub 2017 May 13.
Endocardial mapping of the left ventricle (LV) using the NOGA® XP Cardiac Navigation System can identify chronically ischemic and viable myocardium in patients with coronary artery disease by generating electromechanical maps. These maps are very useful when targeting myocardial tissue for injection of stem cells. We present the case of a woman who developed a perforation at the site of an LV aneurysm during NOGA mapping prior to the transendocardial injection of stem cells, as part of a multicenter clinical trial. The presence of an LV aneurysm is currently not a contraindication (or caution) to the use the NOGA mapping catheter. As the field of stem cell therapy evolves and the use of this technique increases, operators must be aware that the presence of an LV aneurysm may increase the risk of perforation during a NOGA mapping procedure.
使用NOGA® XP心脏导航系统对左心室（LV）进行心内膜标测，通过生成机电图可识别冠心病患者的慢性缺血心肌和存活心肌。在将干细胞注射到心肌组织作为靶点时，这些图非常有用。作为一项多中心临床试验的一部分，我们报告了一名女性患者的病例，该患者在经心内膜注射干细胞之前，在NOGA标测过程中左心室动脉瘤部位发生穿孔。目前，左心室动脉瘤的存在并非使用NOGA标测导管的禁忌证（或注意事项）。随着干细胞治疗领域的发展以及该技术使用的增加，操作人员必须意识到左心室动脉瘤的存在可能会增加NOGA标测过程中穿孔的风险。
