Beverly Anair, Brovman Ethan Y, Urman Richard D
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA, USA.
Center for Perioperative Research, Brigham and Women's Hospital, Boston, MA, USA.
Geriatr Orthop Surg Rehabil. 2017 Jun;8(2):78-86. doi: 10.1177/2151458516685826. Epub 2017 Feb 15.
Emergency hip surgery generally has worse outcomes than elective hip surgery, even when adjusted for patient and surgical factors. Do-not-resuscitate (DNR) status patients are typically at higher perioperative risk and undergo a narrow range of surgical procedures. We aimed to compare the outcomes after hip surgery of differing degrees of urgency in this cohort.
Using National Surgical Quality Improvement Program (NSQIP) data, we conducted univariate and multivariate analyses comparing outcomes of DNR status patients after emergency and nonemergency hip surgery (2007-2013). We conducted a subanalysis of mortality in elective versus nonelective cases (elective variable introduced from 2011).
Of 668 hip surgery cases in DNR status patients, 210 (31.4%) were emergency and 458 (68.8%) were nonemergency. There were no significant associations between emergency and nonemergency surgery regarding patient demographics, comorbidities, functional capacity, anesthesia type, or operative duration. There was no significant difference in the 30-day postoperative mortality between emergency (21.4%) and nonemergency (16.4%) or between elective (19.6%) and nonelective (18.3%) hip fracture surgeries performed in patients with preexisting DNR status. Morbidity patterns in emergency vs nonemergency cases demonstrated no significant differences, with the commonest 3 complications being transfusion (21.0% and 21.4%, respectively), urinary tract infection (9.5% and 7.9%, respectively), and pneumonia (both at 5.2%). The 30-day home discharge rates were low at 4.7% and 5.6%, respectively. Multivariate analysis demonstrated no significant associations between emergency and nonemergency surgery for mortality, discharge destination, length of stay or complications, except perioperative myocardial infarction (3.7% vs 1.3%, < .04).
For patients with DNR status, both emergent and non-emergent hip surgery carries high mortality, greatly exceeding rates predicted for that patient by American College of Surgeons NSQIP risk calculators. Morbidity rates and patterns for patients with DNR status are also similar in emergency and nonemergency groups. These data may be useful in discussing risk and obtaining adequately informed consent in DNR patients undergoing hip surgery.
即使对患者和手术因素进行了调整,急诊髋关节手术的总体预后通常也比择期髋关节手术差。“不要复苏”(DNR)状态的患者通常围手术期风险更高,且接受的手术范围较窄。我们旨在比较该队列中不同紧急程度的髋关节手术后的预后情况。
利用国家外科质量改进计划(NSQIP)的数据,我们进行了单因素和多因素分析,比较了DNR状态患者在急诊和非急诊髋关节手术后的预后情况(2007 - 2013年)。我们对择期与非择期病例的死亡率进行了亚组分析(择期变量从2011年开始引入)。
在668例DNR状态患者的髋关节手术病例中,210例(31.4%)为急诊手术,458例(68.8%)为非急诊手术。急诊手术与非急诊手术在患者人口统计学、合并症、功能状态、麻醉类型或手术时长方面均无显著关联。对于已有DNR状态的患者,急诊髋关节手术(21.4%)和非急诊髋关节手术(16.4%)之间,以及择期髋关节骨折手术(19.6%)和非择期髋关节骨折手术(18.3%)之间,术后30天死亡率均无显著差异。急诊与非急诊病例的并发症模式无显著差异,最常见的3种并发症分别是输血(分别为21.0%和21.4%)、尿路感染(分别为9.5%和7.9%)以及肺炎(均为5.2%)。30天内出院回家的比例较低,分别为4.7%和5.6%。多因素分析表明,急诊手术与非急诊手术在死亡率、出院去向、住院时长或并发症方面均无显著关联,但围手术期心肌梗死除外(3.7%对1.3%,P < 0.04)。
对于DNR状态的患者,急诊和非急诊髋关节手术的死亡率均很高,大大超过了美国外科医师学会NSQIP风险计算器为该类患者预测的死亡率。急诊组和非急诊组中DNR状态患者的并发症发生率及模式也相似。这些数据可能有助于在与接受髋关节手术的DNR患者讨论风险并获得充分知情同意时提供参考。