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对于接受髋部骨折手术的患者,不进行心肺复苏状态是一个独立的风险因素。

Do-Not-Resuscitate status as an independent risk factor for patients undergoing surgery for hip fracture.

作者信息

Brovman Ethan Y, Pisansky Andrew J, Beverly Anair, Bader Angela M, Urman Richard D

机构信息

Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women's Hospital, Boston, MA 02115, United States.

出版信息

World J Orthop. 2017 Dec 18;8(12):902-912. doi: 10.5312/wjo.v8.i12.902.

Abstract

AIM

To determine morbidity and mortality in hip fracture patients and also to assess for any independent associations between Do-Not-Resuscitate (DNR) status and increased post-operative morbidity and mortality in patients undergoing surgical repair of hip fractures.

METHODS

We conducted a propensity score matched retrospective analysis using de-identified data from the American College of Surgeons' National Surgical Quality Improvement Project (ACS NSQIP) for all patients undergoing hip fracture surgery over a 7 year period in hospitals across the United States enrolled in the ACS NSQIP with and without DNR status. We measured patient demographics including DNR status, co-morbidities, frailty and functional baseline, surgical and anaesthetic procedure data, post-operative morbidity/complications, length of stay, discharge destination and mortality.

RESULTS

Of 9218 patients meeting the inclusion criteria, 13.6% had a DNR status, 86.4% did not. Mortality was higher in the DNR compared to the non-DNR group, at 15.3% 8.1% and propensity score matched multivariable analysis demonstrated that DNR status was independently associated with mortality (OR = 2.04, 95%CI: 1.46-2.86, < 0.001). Additionally, analysis of the propensity score matched cohort demonstrated that DNR status was associated with a significant, but very small increased likelihood of post-operative complications (0.53 0.43 complications per episode; OR = 1.21; 95%CI: 1.04-1.41, = 0.004). Cardiopulmonary resuscitation and unplanned reintubation were significantly less likely in patients with DNR status.

CONCLUSION

While DNR status patients had higher rates of post-operative complications and mortality, DNR status itself was not otherwise associated with increased morbidity. DNR status appears to increase 30-d mortality ceilings of care in keeping with a DNR status, including withholding reintubation and cardiopulmonary resuscitation.

摘要

目的

确定髋部骨折患者的发病率和死亡率,并评估“不要复苏”(DNR)状态与接受髋部骨折手术修复患者术后发病率和死亡率增加之间是否存在任何独立关联。

方法

我们使用来自美国外科医师学会国家外科质量改进项目(ACS NSQIP)的去识别数据进行了倾向评分匹配回顾性分析,该数据涉及在美国参与ACS NSQIP的医院中7年内接受髋部骨折手术的所有患者,包括有和没有DNR状态的患者。我们测量了患者人口统计学特征,包括DNR状态、合并症、虚弱程度和功能基线、手术和麻醉程序数据、术后发病率/并发症、住院时间、出院目的地和死亡率。

结果

在符合纳入标准的9218例患者中,13.6%有DNR状态,86.4%没有。DNR组的死亡率高于非DNR组,分别为15.3%和8.1%,倾向评分匹配多变量分析表明DNR状态与死亡率独立相关(OR = 2.04,95%CI:1.46 - 2.86,P < 0.001)。此外,倾向评分匹配队列分析表明,DNR状态与术后并发症的可能性显著但非常小的增加相关(每例0.53对0.43并发症;OR = 1.21;95%CI:1.04 - 1.41,P = 0.004)。DNR状态的患者进行心肺复苏和非计划再插管的可能性显著降低。

结论

虽然有DNR状态的患者术后并发症和死亡率较高,但DNR状态本身与发病率增加并无其他关联。DNR状态似乎会增加30天死亡率,符合DNR状态下的护理上限,包括不进行再插管和心肺复苏。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/70cb/5745433/9b0db4f27920/WJO-8-902-g001.jpg

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