La Grutta Ludovico, Toia Patrizia, Maffei Erica, Cademartiri Filippo, Lagalla Roberto, Midiri Massimo
Department of Radiology, DIBIMED, University of Palermo, Palermo, Italy.
Department of Radiology, Montreal Heart Institute/Universitè de Montreal, Montreal, Canada.
Cardiovasc Diagn Ther. 2017 Apr;7(2):171-188. doi: 10.21037/cdt.2017.03.18.
Myocardial infarction (MI) is a major cause of death and disability worldwide. The incidence is not expected to diminish, despite better prevention, diagnosis and treatment, because of the ageing population in industrialized countries and unhealthy lifestyles in developing countries. Nowadays it is highly requested an imaging tool able to evaluate MI and viability. Technology improvements determined an expansion of clinical indications from coronary plaque evaluation to functional applications (perfusion, ischemia and viability after MI) integrating additional phases and information in the mainstream examination. Cardiac computed tomography (CCT) and cardiac MR (CMR) employ different contrast media, but may characterize MI with overlapping imaging findings due to the similar kinetics and tissue distribution of gadolinium and iodinated contrast media. CCT may detect first-pass perfusion defects, dynamic perfusion after pharmacological stress, and delayed enhancement (DE) of non-viable territories.
心肌梗死(MI)是全球范围内死亡和残疾的主要原因。尽管在预防、诊断和治疗方面有所改善,但由于工业化国家人口老龄化以及发展中国家不健康的生活方式,预计发病率不会降低。如今,迫切需要一种能够评估心肌梗死和心肌活力的成像工具。技术进步使得临床适应症从冠状动脉斑块评估扩展到功能应用(心肌梗死后的灌注、缺血和心肌活力),在主流检查中整合了更多阶段和信息。心脏计算机断层扫描(CCT)和心脏磁共振成像(CMR)使用不同的造影剂,但由于钆和碘化造影剂的动力学和组织分布相似,可能会有重叠的成像表现来表征心肌梗死。CCT可以检测首过灌注缺损、药物负荷后的动态灌注以及无活力区域的延迟强化(DE)。