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[缺铁:识别与治疗]

[Iron deficiency : Recognition and treatment].

作者信息

von Haehling S, Ottenjann H, Anker S D

机构信息

Klinik für Kardiologie und Pneumologie, Herzzentrum Göttingen, Universitätsmedizin Göttingen, Georg-August-Universität, Göttingen, Deutschland.

Deutsches Zentrum für Herz- und Kreislaufforschung, Standort Göttingen, Göttingen, Deutschland.

出版信息

Internist (Berl). 2017 Jun;58(6):627-638. doi: 10.1007/s00108-017-0242-z.

DOI:10.1007/s00108-017-0242-z
PMID:28540476
Abstract

Iron deficiency does not always receive sufficient attention in daily clinical practice. Diagnostic and treatment possibilities are underutilized. This leads to a negative impact on patients' quality of life, exercise capacity, and treatment response, especially in patients with chronic diseases. In this overview, important diagnostic parameters that should be assessed to detect iron deficiency are outlined. In addition, important laboratory parameters are provided. Furthermore, the necessity for early and sufficient iron supplementation for various chronic diseases is presented. In addition, the risks and benefits of currently available oral and intravenous options for iron treatment are outlined.

摘要

在日常临床实践中,缺铁问题并不总是能得到足够的重视。诊断和治疗的可能性未得到充分利用。这会对患者的生活质量、运动能力和治疗反应产生负面影响,尤其是对患有慢性疾病的患者。在本综述中,概述了检测缺铁时应评估的重要诊断参数。此外,还提供了重要的实验室参数。此外,还阐述了针对各种慢性疾病进行早期和充分补铁的必要性。此外,还概述了目前可用的口服和静脉补铁治疗方案的风险和益处。

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Prevalence and clinical impact of iron deficiency and anaemia among outpatients with chronic heart failure: The PrEP Registry.慢性心力衰竭门诊患者中铁缺乏和贫血的患病率及临床影响:PrEP注册研究
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射血分数保留的心力衰竭患者的肌肉减少症:对肌肉力量、运动能力和生活质量的影响。
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Eur J Heart Fail. 2016 Aug;18(8):891-975. doi: 10.1002/ejhf.592. Epub 2016 May 20.
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Incidence of anemia in patients diagnosed with solid tumors receiving chemotherapy, 2010-2013.2010 - 2013年接受化疗的实体瘤诊断患者的贫血发生率
Clin Epidemiol. 2016 Apr 18;8:61-71. doi: 10.2147/CLEP.S89480. eCollection 2016.
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[Diagnostic and treatment principles of iron deficiency anaemia].
MMW Fortschr Med. 2015 Oct 22;157(18):56-8.
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Antianemic Treatment of Cancer Patients in German Routine Practice: Data from a Prospective Cohort Study-The Tumor Anemia Registry.德国常规医疗中癌症患者的抗贫血治疗:来自一项前瞻性队列研究——肿瘤贫血登记处的数据。
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Effects of intravenous iron therapy in iron-deficient patients with systolic heart failure: a meta-analysis of randomized controlled trials.静脉铁剂治疗缺铁性收缩性心力衰竭患者的效果:随机对照试验的荟萃分析。
Eur J Heart Fail. 2016 Jul;18(7):786-95. doi: 10.1002/ejhf.473. Epub 2016 Jan 28.
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Anemia of Chronic Disease and Iron Deficiency Anemia in Inflammatory Bowel Diseases: Pathophysiology, Diagnosis, and Treatment.炎症性肠病中的慢性病贫血和缺铁性贫血:病理生理学、诊断与治疗
Inflamm Bowel Dis. 2016 May;22(5):1198-208. doi: 10.1097/MIB.0000000000000648.
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The Important Role for Intravenous Iron in Perioperative Patient Blood Management in Major Abdominal Surgery: A Randomized Controlled Trial.静脉铁剂在腹部大手术围手术期患者血液管理中的重要作用:一项随机对照试验
Ann Surg. 2016 Jul;264(1):41-6. doi: 10.1097/SLA.0000000000001646.