[β-肾上腺素能受体在胃、幽门括约肌和十二指肠对血清素给药的平滑肌反应中的作用]
[The role of the beta-adrenoreceptors in the smooth-muscle reactions of the stomach, pyloric sphincter and duodenum to serotonin administration].
作者信息
Shemerovskiĭ K A, Ovsiannikov V I
出版信息
Fiziol Zh SSSR Im I M Sechenova. 1988 Dec;74(12):1786-93.
Subcutaneous administration of serotonin (10 mg/kg) altered myoelectrical activity of the stomach, pylorus and duodenum in rabbits causing a discoordination of gastroduodenal motor activity. During activation of beta-Adrenoceptors serotonin induced discoordination superimposed on disturbance of normal coordination of the stomach, pylorus and duodenum induced with isopropylnoradrenaline. beta-Adrenoceptor blockade decreased the degree of serotonin-induced discoordination between motility of the stomach and duodenum as concerns the rhythmic component of their activity.
皮下注射血清素（10毫克/千克）会改变家兔胃、幽门和十二指肠的肌电活动，导致胃十二指肠运动活动失调。在β-肾上腺素能受体激活过程中，血清素诱导的失调叠加在异丙肾上腺素诱导的胃、幽门和十二指肠正常协调性紊乱之上。β-肾上腺素能受体阻断降低了血清素诱导的胃和十二指肠运动之间在其活动节律成分方面的失调程度。
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