Shemerovskiĭ K A, Ovsiannikov V I
Fiziol Zh SSSR Im I M Sechenova. 1986 Apr;72(4):458-65.
In chronic experiments on rabbits, i.v. administration of the pentagastrin (0.01-1.0 micrograms/kg) exerted inhibitory effects on the myoelectrical activity of the pylorus and stomach, whereas the effect of pentagastrin on the duodenum was rather activating. The threshold dose of pentagastrin for pylorus was 5 times smaller than for the duodenum and 10 times smaller than for the stomach. Possible mechanisms of the pentagastrin effect on the contractile activity of the pylorus, stomach and duodenum smooth muscles, are discussed.
在对兔子进行的慢性实验中，静脉注射五肽胃泌素（0.01 - 1.0微克/千克）对幽门和胃的肌电活动产生抑制作用，而五肽胃泌素对十二指肠的作用则具有激活作用。五肽胃泌素对幽门的阈剂量比对十二指肠的小5倍，比对胃的小10倍。文中讨论了五肽胃泌素对幽门、胃和十二指肠平滑肌收缩活动产生作用的可能机制。
