Akl Kamal, Hazza Issa
Department of Pediatrics, Jordan University Hospital; Department of Pediatrics, Faculty of Medicine, College of Medicine, University of Jordan, Amman, Jordan.
Department of Pediatrics, Section of Pediatric Nephrology, Queen Rania Children Hospital, Amman, Jordan.
Saudi J Kidney Dis Transpl. 2017 May-Jun;28(3):589-592. doi: 10.4103/1319-2442.206457.
The practice of pediatric nephrology in a developing country such as Jordan is governed by social, cultural, and economic issues. The prevalence of consanguinity contributes to the emergence of rare heredofamilial disorders and congenital anomalies of the kidneys and urinary tract. Epigenetic factors modify underlying genetic defect predisposing to symptomatic crystalluria. Future research should be directed at prevention.
在约旦这样的发展中国家，儿科肾脏病学的实践受到社会、文化和经济问题的制约。近亲结婚的盛行导致了罕见的遗传家族性疾病以及肾脏和尿路先天性异常的出现。表观遗传因素会改变潜在的遗传缺陷，从而易引发症状性结晶尿。未来的研究应着眼于预防。
