Resnekov O, Ben-Asher E, Bengal E, Choder M, Hay N, Kessler M, Ragimov N, Seiberg M, Skolnik-David H, Aloni Y
Department of Genetics, Weizmann Institute of Science, Rehovot, Israel.
Gene. 1988 Dec 10;72(1-2):91-104. doi: 10.1016/0378-1119(88)90130-8.
Three experimental systems: isolated nuclei, cell-free reactions and whole cells were used for defining and characterizing cis and trans elements which regulate the block of transcription elongation in animal viruses and cells. In addition we have presented models for transcription termination within and at the end of a gene, which are consistent with the available information on the transcription bubble propagated during transcription elongation and can explain the modes of transcription termination described for various eukaryotic genes.
分离的细胞核、无细胞反应体系和完整细胞，以定义和表征调控动物病毒和细胞中转录延伸受阻的顺式和反式元件。此外，我们还提出了基因内部和末端转录终止的模型，这些模型与转录延伸过程中传播的转录泡的现有信息一致，并且可以解释各种真核基因所描述的转录终止模式。
