铑（III）催化醛与亚硝基化合物的双边环化反应，生成不对称吖啶，该反应通过一个瞬态导向基团实现碳-氢官能化。
Rh(iii)-Catalyzed bilateral cyclization of aldehydes with nitrosos toward unsymmetrical acridines proceeding with C-H functionalization enabled by a transient directing group.
作者信息
Hu Weiming, Zheng Qingheng, Sun Song, Cheng Jiang
机构信息
School of Petrochemical Engineering, Jiangsu Key Laboratory of Advanced Catalytic Materials & Technology, and Institute for Natural and Synthetic Organic Chemistry, Changzhou University, Changzhou 213164, P. R. China.
出版信息
Chem Commun (Camb). 2017 Jun 6;53(46):6263-6266. doi: 10.1039/c7cc03006a.
A Rh(iii)-catalyzed bilateral cyclization was developed for the efficient construction of acridines proceeding with C-H functionalization whereby in situ formation and removal of an imino transient directing group in the presence of catalytic amount of BnNH are achieved. In this transformation, a sequential Rh(iii)-catalyzed C-H amination, cyclization, and aromatization process was involved.
开发了一种铑（III）催化的双边环化反应，用于通过C-H官能化高效构建吖啶，从而在催化量的苄胺存在下实现亚氨基瞬态导向基团的原位形成和去除。在该转化过程中，涉及了铑（III）催化的C-H胺化、环化和芳构化的连续过程。
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