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中东呼吸综合征冠状病毒（MERS-CoV）感染在免疫功能低下宿主中的非典型表现。

Atypical presentations of MERS-CoV infection in immunocompromised hosts.

作者信息

Kim Si-Ho, Ko Jae-Hoon, Park Ga Eun, Cho Sun Young, Ha Young Eun, Kang Ji-Man, Kim Yae-Jean, Huh Hee Jae, Ki Chang-Seok, Jeong Byeong-Ho, Park Jinkyeong, Jang Jun Ho, Kim Won Seog, Kang Cheol-In, Chung Doo Ryeon, Song Jae-Hoon, Peck Kyong Ran

机构信息

Division of Infectious Diseases, Department of Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 135-710, Republic of Korea.

Department of Pediatrics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

J Infect Chemother. 2017 Nov;23(11):769-773. doi: 10.1016/j.jiac.2017.04.004. Epub 2017 May 23.

DOI:10.1016/j.jiac.2017.04.004
PMID:28545936
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7129274/
Abstract

During the 2015 Korean MERS outbreak, we experienced atypical presentations of MERS-CoV infections in three immunocompromised hosts that warranted exceptional management. Case 1 showed delayed symptom development after a four-day asymptomatic period, Case 2 experienced a 20-day incubation period, and Case 3 exhibited persistent viral shedding without clinical deterioration. Recognizing these exceptions is extremely important in the management of MERS-CoV-exposed or -infected patients and for control of potential MERS outbreaks.

摘要

在2015年韩国中东呼吸综合征疫情期间，我们在三名免疫功能低下的宿主中遇到了中东呼吸综合征冠状病毒感染的非典型表现，需要特殊处理。病例1在四天无症状期后出现症状延迟发展，病例2经历了20天的潜伏期，病例3出现持续病毒脱落但无临床恶化。认识到这些特殊情况对于管理接触或感染中东呼吸综合征冠状病毒的患者以及控制潜在的中东呼吸综合征疫情极为重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/b1ffcf5688d2/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/d68dfa536a60/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/af7ba8c839b9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/74bc3050dc41/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/b1ffcf5688d2/gr4_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/d68dfa536a60/gr1_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/af7ba8c839b9/gr2_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/74bc3050dc41/gr3_lrg.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/beb4/7129274/b1ffcf5688d2/gr4_lrg.jpg

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