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Peripheral Blood-Derived Mesenchymal Stem Cells Promote A2 Phenotype Polarization in Astrocytes via TGF-β-Mediated PI3K/Akt Pathway Activation.外周血来源的间充质干细胞通过TGF-β介导的PI3K/Akt信号通路激活促进星形胶质细胞向A2表型极化。
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Therapeutic Applications of Engineered Mesenchymal Stromal Cells for Enhanced Angiogenesis in Cardiac and Cerebral Ischemia.工程化间充质基质细胞在心脏和脑缺血中增强血管生成的治疗应用。
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Prostaglandin E hydrogel improves cutaneous wound healing via M2 macrophages polarization.前列腺素 E 水凝胶通过 M2 巨噬细胞极化改善皮肤伤口愈合。
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Recent Progress in Stem Cell Modification for Cardiac Regeneration.用于心脏再生的干细胞修饰的最新进展
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本文引用的文献

1
PIM1-minicircle as a therapeutic treatment for myocardial infarction.PIM1微小环作为心肌梗死的一种治疗方法。
PLoS One. 2017 Mar 21;12(3):e0173963. doi: 10.1371/journal.pone.0173963. eCollection 2017.
2
Fabrication of Synthetic Mesenchymal Stem Cells for the Treatment of Acute Myocardial Infarction in Mice.用于治疗小鼠急性心肌梗死的合成间充质干细胞的制备
Circ Res. 2017 May 26;120(11):1768-1775. doi: 10.1161/CIRCRESAHA.116.310374. Epub 2017 Mar 15.
3
Repeated doses of cardiac mesenchymal cells are therapeutically superior to a single dose in mice with old myocardial infarction.在患有陈旧性心肌梗死的小鼠中，重复剂量的心脏间充质细胞在治疗上优于单次剂量。
Basic Res Cardiol. 2017 Mar;112(2):18. doi: 10.1007/s00395-017-0606-5. Epub 2017 Feb 16.
4
Synthetic (polymer) biology (membrane): functionalization of polymer scaffolds for membrane proteins.合成（聚合物）生物学（膜）：用于膜蛋白的聚合物支架功能化
Curr Opin Biotechnol. 2017 Aug;46:51-56. doi: 10.1016/j.copbio.2016.10.012. Epub 2017 Feb 7.
5
Concise review: immunomodulatory properties of mesenchymal stem cells in cellular transplantation: update, controversies, and unknowns.简明综述：间充质干细胞在细胞移植中的免疫调节特性：更新、争议和未知。
Stem Cells Transl Med. 2012 Mar;1(3):200-5. doi: 10.5966/sctm.2011-0012. Epub 2012 Mar 12.
6
Harnessing the mesenchymal stem cell secretome for the treatment of cardiovascular disease.利用间充质干细胞 secretome 治疗心血管疾病。
Cell Stem Cell. 2012 Mar 2;10(3):244-58. doi: 10.1016/j.stem.2012.02.005.
7
Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease.间质干细胞外泌体：一种基于干细胞的新型心血管疾病治疗方法。
Regen Med. 2011 Jul;6(4):481-92. doi: 10.2217/rme.11.35.
8
Rebuilding the damaged heart: the potential of cytokines and growth factors in the treatment of ischemic heart disease.重建受损心脏：细胞因子和生长因子在缺血性心脏病治疗中的潜力。
J Am Coll Cardiol. 2010 Oct 12;56(16):1287-97. doi: 10.1016/j.jacc.2010.05.039.
9
Animal cells connected by nanotubes can be electrically coupled through interposed gap-junction channels.通过纳米管连接的动物细胞可以通过中间的间隙连接通道进行电偶联。
Proc Natl Acad Sci U S A. 2010 Oct 5;107(40):17194-9. doi: 10.1073/pnas.1006785107. Epub 2010 Sep 20.
10
Bone marrow mesenchymal stem cells stimulate cardiac stem cell proliferation and differentiation.骨髓间充质干细胞刺激心脏干细胞的增殖和分化。
Circ Res. 2010 Oct 1;107(7):913-22. doi: 10.1161/CIRCRESAHA.110.222703. Epub 2010 Jul 29.

Synthetic MSC? Nothing Beats the Real Thing.

作者信息

Monsanto Megan M, Wang Bingyan J, Sussman Mark A

机构信息

From the Department of Biology, San Diego State University Heart Institute, San Diego State University, CA.

出版信息

Circ Res. 2017 May 26;120(11):1694-1695. doi: 10.1161/CIRCRESAHA.117.310986.

DOI:10.1161/CIRCRESAHA.117.310986
PMID:28546347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5555396/
Abstract
摘要