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GPR75 Identified as the First 20-HETE Receptor: A Chemokine Receptor Adopted by a New Family.

作者信息

Fan Fan, Roman Richard J

机构信息

From the Department of Pharmacology and Toxicology, University of Mississippi Medical Center, Jackson.

出版信息

Circ Res. 2017 May 26;120(11):1696-1698. doi: 10.1161/CIRCRESAHA.117.311022.

DOI:10.1161/CIRCRESAHA.117.311022
PMID:28546348
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5766006/
Abstract
摘要

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本文引用的文献

1
20-HETE Signals Through G-Protein-Coupled Receptor GPR75 (G) to Affect Vascular Function and Trigger Hypertension.20-羟基二十碳四烯酸(20-HETE)通过G蛋白偶联受体GPR75发出信号,影响血管功能并引发高血压。
Circ Res. 2017 May 26;120(11):1776-1788. doi: 10.1161/CIRCRESAHA.116.310525. Epub 2017 Mar 21.
2
Recent developments on the vascular effects of 20-hydroxyeicosatetraenoic acid.20-羟基二十碳四烯酸血管效应的最新进展
Curr Opin Nephrol Hypertens. 2017 Mar;26(2):74-82. doi: 10.1097/MNH.0000000000000302.
3
Molecular mechanisms and cell signaling of 20-hydroxyeicosatetraenoic acid in vascular pathophysiology.20-羟二十碳四烯酸在血管病理生理学中的分子机制和细胞信号转导。
Front Biosci (Landmark Ed). 2016 Jun 1;21(7):1427-63. doi: 10.2741/4465.
4
Vascular actions of 20-HETE.20-羟基二十碳四烯酸的血管作用
Prostaglandins Other Lipid Mediat. 2015 Jul;120:9-16. doi: 10.1016/j.prostaglandins.2015.03.002. Epub 2015 Mar 23.
5
Cytochrome P450 eicosanoids in hypertension and renal disease.高血压和肾脏疾病中的细胞色素P450类花生酸
Curr Opin Nephrol Hypertens. 2015 Jan;24(1):37-46. doi: 10.1097/MNH.0000000000000088.
6
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Diabetologia. 2013 Nov;56(11):2467-76. doi: 10.1007/s00125-013-3022-x. Epub 2013 Aug 27.
7
Protein kinase C pharmacology: refining the toolbox.蛋白激酶 C 药理学:完善工具盒。
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20-HETE activates the Raf/MEK/ERK pathway in renal epithelial cells through an EGFR- and c-Src-dependent mechanism.20-羟基二十碳四烯酸(20-HETE)通过表皮生长因子受体(EGFR)和c-Src依赖性机制激活肾上皮细胞中的Raf/丝裂原活化蛋白激酶/细胞外信号调节激酶(Raf/MEK/ERK)信号通路。
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Synergistic activation of vascular TRPC6 channel by receptor and mechanical stimulation via phospholipase C/diacylglycerol and phospholipase A2/omega-hydroxylase/20-HETE pathways.受体和机械刺激通过磷脂酶C/二酰基甘油以及磷脂酶A2/ω-羟化酶/20-羟基二十碳四烯酸途径对血管瞬时受体电位通道6(TRPC6)进行协同激活。
Circ Res. 2009 Jun 19;104(12):1399-409. doi: 10.1161/CIRCRESAHA.108.193227. Epub 2009 May 14.
10
Effect of 20-HETE inhibition on infarct volume and cerebral blood flow after transient middle cerebral artery occlusion.20-羟基二十碳四烯酸(20-HETE)抑制对短暂性大脑中动脉闭塞后梗死体积和脑血流量的影响。
J Cereb Blood Flow Metab. 2009 Mar;29(3):629-39. doi: 10.1038/jcbfm.2008.156. Epub 2008 Dec 24.