Avello L Marcia, Pastene N Edgar, Fernández R Pola, Córdova M Pia
Departamento de Farmacia, Facultad de Farmacia, Universidad de Concepción, Concepción, Chile,
Rev Med Chil. 2017 Mar;145(3):360-367. doi: 10.4067/S0034-98872017000300010.
Cannabis sativa (marihuana) is considered an illicit drug due to its psychoactive properties. Recently, the Chilean government opened to the use cannabis in the symptomatic treatment of some patients. The biological effects of cannabis render it useful for the complementary treatment of specific clinical situations such as chronic pain. We retrieved scientific information about the analgesic properties of cannabis, using it as a safe drug. The drug may block or inhibit the transmission of nervous impulses at different levels, an effect associated with pain control. Within this context and using adequate doses, forms and administration pathways, it can be used for chronic pain management, considering its effectiveness and low cost. It could also be considered as an alternative in patients receiving prolonged analgesic therapies with multiple adverse effects.
由于其精神活性特性,大麻被视为非法药物。最近,智利政府开始允许在某些患者的对症治疗中使用大麻。大麻的生物学效应使其可用于特定临床情况(如慢性疼痛)的辅助治疗。我们检索了有关大麻镇痛特性的科学信息,将其作为一种安全药物使用。该药物可能在不同水平阻断或抑制神经冲动的传递,这种效应与疼痛控制相关。在此背景下,使用适当的剂量、剂型和给药途径,考虑到其有效性和低成本,它可用于慢性疼痛管理。对于接受长期镇痛治疗且有多种不良反应的患者,它也可被视为一种替代选择。