Boccia E, Gizzi A, Cherubini C, Nestola M G C, Filippi S
Max Planck Institute for Dynamics and Self-Organization, Am Faßberg 17, Göttingen, 37077, Germany.
Department of Engineering, Universitá Campus Bio-Medico di Roma, Via A. del Portillo 21, Rome 00128, Italy.
Int J Numer Method Biomed Eng. 2018 Jan;34(1). doi: 10.1002/cnm.2900. Epub 2017 Jul 19.
A subject-specific 3-dimensional viscoelastic finite element model of the human head-neck system is presented and investigated based on computed tomography and magnetic resonance biomedical images. Ad hoc imaging processing tools are developed for the reconstruction of the simulation domain geometry and the internal distribution of bone and soft tissues. Material viscoelastic properties are characterized point-wise through an image-based interpolating function used then for assigning the constitutive prescriptions of a heterogenous viscoelastic continuum model. The numerical study is conducted both for modal and time-dependent analyses, compared with similar studies and validated against experimental evidences. Spatiotemporal analyses are performed upon different exponential swept-sine wave-localized stimulations. The modeling approach proposes a generalized, patient-specific investigation of sound wave transmission and attenuation within the human head-neck system comprising skull and brain tissues. Model extensions and applications are finally discussed.
