a Institute of Experimental Physics, Slovak Academy of Sciences , Košice , Slovakia.
b Lesya Ukrainka Eastern European National University , Lutsk , Ukraine.
Crit Rev Anal Chem. 2017 Nov 2;47(6):474-489. doi: 10.1080/10408347.2017.1332973. Epub 2017 May 26.
The use of electroanalytical techniques for the determination of statins (Atorvastatin, Fluvastatin, Lovastatin, Pitavastatin, Pravastatin, Rosuvastatin and Simvastatin) is reviewed covering the period from 1997 to 2016. Among all of the published electrochemical methods, voltammetry and polarography are the most popular techniques for the determination of statins, and both are used for the analysis of pharmaceutical dosage forms and biological samples. The determination of statins by a potentiometric method using ion-selective electrodes is reported in only few papers. Сoulometry and conductometry have been not used for the determination of statins till date. Current trends in developing new electrochemical methods for the analysis of statins are discussed.
电化学技术在他汀类药物（阿托伐他汀、氟伐他汀、洛伐他汀、匹伐他汀、普伐他汀、罗苏伐他汀和辛伐他汀）测定中的应用综述，涵盖了 1997 年至 2016 年的相关文献。在所有已发表的电化学方法中，伏安法和极谱法是用于测定他汀类药物的最常用技术，并且这两种方法都被用于药物制剂和生物样本的分析。仅少数文献报道了使用离子选择性电极的电位法测定他汀类药物。库仑法和电导法至今尚未用于测定他汀类药物。本文讨论了用于分析他汀类药物的新电化学方法的最新发展趋势。
