中国西南部四川省不同地区汉族人群中17个Y染色体STR基因座的单倍型多样性
Haplotype diversity of 17 Y-chromosome STR loci in Han population from different areas of Sichuan Province, Southwest China.
作者信息
Fan Guangyao, Li Wei, Ye Yi, Li Xuebo, Ge Wendong, Yang Yongqiang, Long Bing
机构信息
The Center for Forensic Science Research, Department of Public Security Technology, Railway Police College, Zhengzhou 450053, China; Department of Forensic Analytical Toxicology, West China School of Basic Science and Forensic Medicine, Sichuan University, Chengdu 610041, Sichuan, China.
The Center for Forensic Science Research, Department of Public Security Technology, Railway Police College, Zhengzhou 450053, China.
出版信息
Leg Med (Tokyo). 2017 May;26:73-75. doi: 10.1016/j.legalmed.2017.03.005. Epub 2017 Mar 30.
The distribution of 17 Y-chromosome short tandem repeat (STR) loci, included in the AmpFlSTR®Yfiler™ amplification kit, were analyzed in six different samplings (N=878) from Sichuan, China. Haplotype diversity and discrimination capacity (DC) values were calculated. Pairwise Rst values were evaluated in AMOVA analysis and visualized through multidimensional scaling (MDS). A total of 547 unique haplotypes were detected. The observed haplotype diversity and discrimination capacity were 0.9995 and 0.7745, respectively. The homogeneity of Sichuan Han population was detected when microareas were analyzed. This population exhibited no significant genetic difference to both of the minorities in reference databases, Mongolian and Manchu, which had been through mass ethnic amalgamation with Sichuan Han population in history.
对中国四川六个不同样本（N = 878）进行分析，这些样本包含在AmpFlSTR®Yfiler™扩增试剂盒中的17个Y染色体短串联重复序列（STR）位点。计算单倍型多样性和鉴别能力（DC）值。在分子方差分析（AMOVA）中评估成对Rst值，并通过多维尺度分析（MDS）进行可视化。共检测到547种独特单倍型。观察到的单倍型多样性和鉴别能力分别为0.9995和0.7745。在分析微区域时检测到四川汉族群体的同质性。该群体与参考数据库中的两个少数民族蒙古族和满族均无显著遗传差异，这两个少数民族在历史上曾与四川汉族群体进行过大规模的民族融合。
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