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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Department of Pharmacology, Medical Sciences Campus, San Juan, Puerto Rico 00936.

Braz J Med Biol Res. 1988;21(6):1225-31.

The role of cAMP on cell-to-cell diffusion of Lucifer Yellow was investigated. It was found that dB-cAMP or isoproterenol increases the junctional permeability appreciably in dog's atrium muscle. 2. This effect which occurs within 85 min seems to be related to an increase in unit channel permeability. Chronic treatment of animals with ephedrine enhances the junctional permeability in vivo. 3. The results support the view that cAMP plays a short-term and long-term regulatory role on junctional permeability.

研究了环磷酸腺苷（cAMP）对荧光黄在细胞间扩散的作用。发现二丁酰环磷酸腺苷（dB-cAMP）或异丙肾上腺素可显著增加犬心房肌的连接通透性。2. 这种在85分钟内出现的效应似乎与单位通道通透性的增加有关。用麻黄碱对动物进行长期处理可在体内增强连接通透性。3. 这些结果支持了cAMP对连接通透性起短期和长期调节作用的观点。

Department of Pharmacology, Medical Sciences Campus, San Juan, Puerto Rico 00936.

Braz J Med Biol Res. 1988;21(6):1225-31.

The role of cAMP on cell-to-cell diffusion of Lucifer Yellow was investigated. It was found that dB-cAMP or isoproterenol increases the junctional permeability appreciably in dog's atrium muscle. 2. This effect which occurs within 85 min seems to be related to an increase in unit channel permeability. Chronic treatment of animals with ephedrine enhances the junctional permeability in vivo. 3. The results support the view that cAMP plays a short-term and long-term regulatory role on junctional permeability.

研究了环磷酸腺苷（cAMP）对荧光黄在细胞间扩散的作用。发现二丁酰环磷酸腺苷（dB-cAMP）或异丙肾上腺素可显著增加犬心房肌的连接通透性。2. 这种在85分钟内出现的效应似乎与单位通道通透性的增加有关。用麻黄碱对动物进行长期处理可在体内增强连接通透性。3. 这些结果支持了cAMP对连接通透性起短期和长期调节作用的观点。