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验证 TAPS-1:一种用于在初级保健中识别不健康物质使用的四项筛查工具。

Validation of the TAPS-1: A Four-Item Screening Tool to Identify Unhealthy Substance Use in Primary Care.

机构信息

Friends Research Institute, 1040 Park Avenue, Suite 103, Baltimore, MD, 21201, USA.

New York University School of Medicine, New York, NY, USA.

出版信息

J Gen Intern Med. 2017 Sep;32(9):990-996. doi: 10.1007/s11606-017-4079-x. Epub 2017 May 26.

Abstract

BACKGROUND

The Tobacco, Alcohol, Prescription Medication, and Other Substance use (TAPS) tool is a combined two-part screening and brief assessment developed for adult primary care patients. The tool's first-stage screening component (TAPS-1) consists of four items asking about past 12-month use for four substance categories, with response options of never, less than monthly, monthly, weekly, and daily or almost daily.

OBJECTIVE

To validate the TAPS-1 in primary care patients.

DESIGN

Participants completed the TAPS tool in self- and interviewer-administered formats, in random order. In this secondary analysis, the TAPS-1 was evaluated against DSM-5 substance use disorder (SUD) criteria to determine optimal cut-points for identifying unhealthy substance use at three severity levels (problem use, mild SUD, and moderate-to-severe SUD).

PARTICIPANTS

Two thousand adult patients at five primary care sites.

MAIN MEASURES

DSM-5 SUD criteria were determined via the modified Composite International Diagnostic Interview. Oral fluid was used as a biomarker of recent drug use.

KEY RESULTS

Optimal frequency-of-use cut-points on the self-administered TAPS-1 for identifying SUDs were ≥ monthly use for tobacco and alcohol (sensitivity = 0.92 and 0.71, specificity = 0.80 and 0.85, AUC = 0.86 and 0.78, respectively) and any reported use for illicit drugs and prescription medication misuse (sensitivity = 0.93 and 0.89, specificity = 0.85 and 0.91, AUC = 0.89 and 0.90, respectively). The performance of the interviewer-administered format was similar. When administered first, the self-administered format yielded higher disclosure rates for past 12-month alcohol use, illicit drug use, and prescription medication misuse. Frequency of use alone did not provide sufficient information to discriminate between gradations of substance use problem severity. Among those who denied drug use on the TAPS-1, less than 4% had a drug-positive biomarker.

CONCLUSIONS

The TAPS-1 can identify unhealthy substance use in primary care patients with a high level of accuracy, and may have utility in primary care for rapid triage.

摘要

背景

TAPS 工具是一种结合了两部分的筛查和简短评估,专为成人初级保健患者开发。该工具的第一阶段筛查部分(TAPS-1)由四个项目组成,询问四个物质类别过去 12 个月的使用情况,回答选项为从未、少于每月、每月、每周和每天或几乎每天。

目的

验证 TAPS-1 在初级保健患者中的有效性。

设计

参与者以自我和访谈者管理的格式随机完成 TAPS 工具,在这项二次分析中,TAPS-1 根据 DSM-5 物质使用障碍(SUD)标准进行评估,以确定识别三种严重程度(问题使用、轻度 SUD 和中度至重度 SUD)下的不健康物质使用的最佳切点。

参与者

五个初级保健地点的 2000 名成年患者。

主要措施

DSM-5 SUD 标准通过改良的综合国际诊断访谈确定。口腔液被用作最近药物使用的生物标志物。

主要结果

自我管理的 TAPS-1 用于识别 SUD 的最佳使用频率切点为每月使用≥烟草和酒精(敏感性分别为 0.92 和 0.71,特异性分别为 0.80 和 0.85,AUC 分别为 0.86 和 0.78),以及任何报告的非法药物和处方药物滥用(敏感性分别为 0.93 和 0.89,特异性分别为 0.85 和 0.91,AUC 分别为 0.89 和 0.90)。访谈者管理格式的性能相似。当首先进行管理时,自我管理格式会提高过去 12 个月酒精使用、非法药物使用和处方药物滥用的披露率。仅使用频率不足以区分物质使用问题严重程度的梯度。在那些在 TAPS-1 上否认药物使用的人中,不到 4%的人有药物阳性生物标志物。

结论

TAPS-1 可以以较高的准确性识别初级保健患者的不健康物质使用情况,并且可能在初级保健中具有快速分诊的实用价值。

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