Wang Chao, Burtis D Brandon, Ding Mingzhou, Mo Jue, Williamson John B, Heilman Kenneth M
a J. Crayton Pruitt Family Department of Biomedical Engineering , University of Florida , Gainesville , FL , USA.
b Department of Neurology , University of Florida, College of Medicine , Gainesville , FL , USA.
J Clin Exp Neuropsychol. 2018 Mar;40(2):198-204. doi: 10.1080/13803395.2017.1332169. Epub 2017 May 28.
BACKGROUND/OBJECTIVES: Prior research has revealed that whereas activation of the left hemisphere primarily increases the activity of the parasympathetic division of the autonomic nervous system, right-hemisphere activation increases the activity of the sympathetic division. In addition, each hemisphere primarily receives retinocollicular projections from the contralateral eye. A prior study reported that pupillary dilation was greater with left- than with right-eye monocular viewing. The goal of this study was to test the alternative hypotheses that this asymmetric pupil dilation with left-eye viewing was induced by activation of the right-hemispheric-mediated sympathetic activity, versus a reduction of left-hemisphere-mediated parasympathetic activity. Thus, this study was designed to learn whether there are changes in hemispheric activation, as measured by alteration of spontaneous alpha activity, during right versus left monocular viewing.
High-density electroencephalography (EEG) was recorded from healthy participants viewing a crosshair with their right, left, or both eyes.
There was a significantly less alpha power over the right hemisphere's parietal-occipital area with left and binocular viewing than with right-eye monocular viewing.
The greater relative reduction of right-hemisphere alpha activity during left than during right monocular viewing provides further evidence that left-eye viewing induces greater increase in right-hemisphere activation than does right-eye viewing.
背景/目的：先前的研究表明，左半球的激活主要增加自主神经系统副交感神经分支的活动，而右半球的激活则增加交感神经分支的活动。此外，每个半球主要接收来自对侧眼睛的视网膜丘脑投射。先前的一项研究报告称，单眼观看时左眼引起的瞳孔扩张比右眼更大。本研究的目的是检验另一种假设，即左眼观看时这种不对称的瞳孔扩张是由右半球介导的交感神经活动激活引起的，还是由左半球介导的副交感神经活动减少引起的。因此，本研究旨在了解在单眼观看右眼和左眼时，通过自发α活动的改变来测量的半球激活是否存在变化。
记录健康参与者用右眼、左眼或双眼观看十字准线时的高密度脑电图（EEG）。
与单眼观看右眼相比，单眼观看左眼和双眼观看时，右半球顶枕区的α功率显著降低。
与单眼观看右眼相比，单眼观看左眼时右半球α活动的相对减少更大，这进一步证明，与右眼观看相比，左眼观看引起右半球激活的增加更大。
