Peters R C, Groen E L, van der Sluis M M, Teunis P F, Wilhelm K A
Laboratory of Comparative Physiology, University of Utrecht, The Netherlands.
Neuroscience. 1988 Dec;27(3):1049-53. doi: 10.1016/0306-4522(88)90209-6.
Denervation-induced changes in the synaptic efficacy of single electroreceptors in catfish (Ictalurus nebulosus, Teleostei) were studied in vivo under alfadolone anaesthesia. At 16 degrees C the following effects were found 48 h post-operatively: (1) the average amplitude of the extra-dermally recorded spikes decreased from 100 to less than 20 microV; (2) the average resting discharge decreased from 40 to less than 25 spikes/s; (3) neither the sensitivity nor the frequency characteristic changed. The results indicate that the resting discharge and the modulation mechanism of sensory synapses are controlled by different biochemical mechanisms. The resting discharge seems to be related to the trophic function of the afferent nerve and to its generator region, whereas the modulation mechanism is apparently associated with the receptor cell.
在阿法多龙麻醉下，于活体状态研究了去神经支配对鲶鱼（美洲鲶，硬骨鱼纲）单个电感受器突触效能的影响。在16摄氏度时，术后48小时发现以下效应：（1）经皮记录的尖峰平均幅度从100微伏降至不足20微伏；（2）平均静息放电频率从40次/秒降至不足25次/秒；（3）敏感性和频率特性均未改变。结果表明，感觉突触的静息放电和调制机制受不同生化机制控制。静息放电似乎与传入神经及其发生器区域的营养功能有关，而调制机制显然与受体细胞相关。
