波兰人群中磷酸乙醇酸磷酸酶（PGP）（酶编号：3.2.3.18）的基因多态性

Genetic polymorphism of phosphoglycolate phosphatase (PGP) (E.C.:3.2.3.18) in the Polish population.

作者信息

Hałasa J, Schlesinger D, Pietraszko M, Mańczak M, Leśko D

机构信息

Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, Wrocław.

出版信息

Arch Immunol Ther Exp (Warsz). 1988;36(6):695-700.

PMID:2855392

Abstract

In a sample of the Polish population of 261 unrelated adults, six types of phosphoglycolate phosphatase (PGP) were encountered. From the distribution of phenotypes obtained, the following frequency of genes was calculated: PGP1 = 0.8429, PGP2 = 0.1399 and PGP3 = 0.0172. PGP types were also determined in 12 families with 30 children and in 55 mother-child pairs. In the group of children the observed distribution of types was consistent with assumed types. The usefulness of this system in disputed paternity cases is as high as 13.52%.

摘要

在261名无亲缘关系的波兰成年人样本中，发现了六种磷酸乙醇酸磷酸酶（PGP）类型。根据获得的表型分布，计算出以下基因频率：PGP1 = 0.8429，PGP2 = 0.1399，PGP3 = 0.0172。还对12个有30个孩子的家庭以及55对母婴进行了PGP类型测定。在儿童组中，观察到的类型分布与假设的类型一致。该系统在亲子鉴定争议案件中的实用性高达13.52%。