Guo Tao, Tan Su-Bei, Wang Ya, Chang Jun
a School of Life Science and Engineering , Lanzhou University of Technology , Lanzhou , China.
b School of Pharmacy , Fudan University , Shanghai , China.
Nat Prod Res. 2018 Jan;32(1):71-76. doi: 10.1080/14786419.2017.1333994. Epub 2017 May 29.
Two new monoterpenoid glycosides, trans-1,8-cineole-3,6-dihydroxy-3-O-β-D-glucopyranoside (1), and 5,9-dihydroxy borneol 2-O-β-D-glucopyranoside (2), together with four known monoterpenoid glycosides (3-6), were isolated from the water-soluble constituents of the fresh rhizome of Tongling White Ginger (Zingiber officinale). Their structures were decisively elucidated by spectroscopic analysis. In vitro tests for antimicrobial activity showed that compounds 1 and 3 possess significant activity against two Gram-positive organisms, Staphylococcus aureus and Staphylococcus epidermidis.
从铜陵白姜(姜科植物)新鲜根茎的水溶性成分中分离得到两个新的单萜糖苷,反式-1,8-桉叶素-3,6-二羟基-3-O-β-D-吡喃葡萄糖苷(1)和5,9-二羟基冰片2-O-β-D-吡喃葡萄糖苷(2),以及四个已知的单萜糖苷(3-6)。通过光谱分析明确了它们的结构。体外抗菌活性测试表明,化合物1和3对两种革兰氏阳性菌金黄色葡萄球菌和表皮葡萄球菌具有显著活性。