Asgar Pour Hossein
AORN J. 2017 Jun;105(6):571-578. doi: 10.1016/j.aorn.2017.04.006.
I conducted a prospective repeated-measure study in the general surgery intensive care unit to investigate the associations among acute postoperative pain, analgesic therapy, and hemodynamic parameters. I selected 33 patients and recorded 84 episodes of pain. I measured intensity of pain and hemodynamic parameters after patients were transferred from the postanesthesia care unit to the general surgery intensive care unit, immediately before analgesic therapy and at 15, 30, and 45 minutes after analgesic therapy. Acute pain increased systolic (SBP), diastolic (DBP), and mean arterial blood pressure (MAP); pulse rate (PR); and arterial oxygen saturation. Fifteen minutes after analgesic therapy, SBP and PR decreased, and DBP, MAP, and oxygen saturation increased. Thirty minutes after therapy, SBP, MAP, and PR decreased, and DBP and oxygen saturation increased. Forty-five minutes after therapy, SBP, MAP, and PR decreased, and DBP and oxygen saturation increased. I saw no significant hemodynamic parameter changes during postoperative episodes of pain.
我在普通外科重症监护病房进行了一项前瞻性重复测量研究，以调查术后急性疼痛、镇痛治疗和血流动力学参数之间的关联。我选取了33名患者，记录了84次疼痛发作情况。在患者从麻醉后护理病房转入普通外科重症监护病房后、镇痛治疗前即刻以及镇痛治疗后15、30和45分钟时，我测量了疼痛强度和血流动力学参数。急性疼痛会使收缩压（SBP）、舒张压（DBP）和平均动脉压（MAP）升高；使脉搏率（PR）升高；并使动脉血氧饱和度升高。镇痛治疗15分钟后，SBP和PR下降，DBP、MAP和血氧饱和度升高。治疗30分钟后，SBP、MAP和PR下降，DBP和血氧饱和度升高。治疗45分钟后，SBP、MAP和PR下降，DBP和血氧饱和度升高。我发现在术后疼痛发作期间血流动力学参数无显著变化。
