Kurtz Steven P, Buttram Mance E, Pagano Maria E, Surratt Hilary L
Center for Applied Research on Substance Use and Health Disparities, Nova Southeastern University, 7255 NE 4th Avenue, Suite 112, Miami, FL 33138, USA.
Department of Psychiatry, Division of Child Psychiatry, Case Western Reserve University, 10524 Euclid Avenue #1155A, Cleveland, OH 44106, USA.
J Subst Abuse Treat. 2017 Jul;78:64-73. doi: 10.1016/j.jsat.2017.05.008. Epub 2017 May 12.
Efficacious interventions to reduce drug use and its consequences for club drug using populations are not apparent in the literature. We tested interviewer- (CAPI) and self-administered (ACASI) comprehensive health and social risk assessments as distinct interventions compared to waitlist control.
750 men and women ages 18-39 with multidrug use and heterosexual behavior were randomized in equal proportions to the three conditions. Instrumentation included well-tested measures of drug use, risky sex, mental distress and substance dependence.
The sample was 56% male; mean age=25. Reported risk behaviors and health consequences did not differ by assessment modality. Adjusted HLM analyses showed a significant main effect of assigned condition on all outcomes. CAPI participants had greater reductions in drug use, risky sex, mental distress and substance dependence symptoms, and greater increases in abstinence, compared to ACASI intervention or control participants at 12months, except that the CAPI and ACASI conditions had similar efficacy for reductions in drug use. Effect sizes for CAPI versus ACASI participants were d=0.2-0.3, and between CAPI and controls d=0.2-0.4. Effect sizes for improved outcomes between ACASI compared to controls were small to non-significant.
The study established the therapeutic benefit of interviewer interaction in reducing risky behavior among this young drug using population. The study demonstrated the efficacy and acceptability of a low threshold intervention in reducing drug use, sexual risk and related co-morbidities among a not-in-treatment young adult population that exhibits severe and complex levels of drug use, but that is also highly resistant to intervention.
在文献中,尚未发现针对减少吸毒及其对俱乐部吸毒人群影响的有效干预措施。我们将访谈式(计算机辅助个人访谈,CAPI)和自我管理式(计算机辅助自我访谈,ACASI)综合健康与社会风险评估作为与等待名单对照相比的不同干预措施进行了测试。
750名年龄在18 - 39岁、有多种药物使用且有异性性行为的男性和女性被等比例随机分配到三种条件下。测量工具包括经过充分测试的药物使用、危险性行为、精神困扰和物质依赖的测量指标。
样本中56%为男性;平均年龄 = 25岁。报告的风险行为和健康后果在评估方式上没有差异。调整后的分层线性模型分析显示,分配条件对所有结果都有显著的主效应。与ACASI干预组或对照组参与者相比,在12个月时,CAPI参与者在药物使用、危险性行为、精神困扰和物质依赖症状方面有更大程度的减少,在禁欲方面有更大程度的增加,但CAPI和ACASI条件在减少药物使用方面具有相似的疗效。CAPI与ACASI参与者之间的效应大小为d = 0.2 - 0.3,CAPI与对照组之间为d = 0.2 - 0.4。ACASI与对照组相比,改善结果的效应大小较小或无显著性差异。
该研究确立了访谈者互动在减少这一年轻吸毒人群危险行为方面的治疗益处。该研究证明了一种低门槛干预措施在减少未接受治疗的年轻成年人群中的药物使用、性风险和相关共病方面的有效性和可接受性,该人群表现出严重且复杂的药物使用水平,但对干预也具有高度抗性。