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肉毒杆菌毒素A治疗迟发性开颅术后头痛:病例系列

Delayed-onset post-craniotomy headache responsive to botulinum toxin A: a case series.

作者信息

Ranoux Danièle, Martiné Gaëlle, Espagne Gaëlle, Salle Henri, Caire François

机构信息

Department of Neurosurgery, CHU Limoges, Limoges, France.

Pain Center, CHU Limoges, Limoges, France.

出版信息

Acta Neurochir (Wien). 2017 Aug;159(8):1375-1378. doi: 10.1007/s00701-017-3215-z. Epub 2017 May 30.

DOI:10.1007/s00701-017-3215-z
PMID:28555271
Abstract

We report here the case of four patients presenting with delayed-onset temporal pain after pterional craniotomy. They reported similar symptoms: attacks of pain over the temporal region, ipsilateral to the operative site, irradiating around the eye and lasting from 10 min to 1 h. All patients had hypertrophy of at least one part of the temporalis muscle. All responded dramatically to botulinum toxin A injection (25 to 50 Botox® units) into the temporalis muscle. We suggest that the headaches were caused by aberrant nerve regeneration following surgical injury to the frontal branch of the facial nerve.

摘要

我们在此报告4例翼点入路开颅术后出现迟发性颞部疼痛的病例。他们报告了相似的症状:手术部位同侧颞部区域发作性疼痛,向眼周放射,持续10分钟至1小时。所有患者颞肌至少有一部分肥厚。所有患者经颞肌注射A型肉毒毒素(25至50单位保妥适®)后均有显著疗效。我们认为,这些头痛是由于面神经额支手术损伤后异常神经再生所致。

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引用本文的文献

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Cluster-Like Headache Secondary to Anamnesis of Sphenoid Ridge Meningioma: A Case Report and Literature Review.蝶骨嵴脑膜瘤病史继发的丛集样头痛:一例报告及文献综述
Front Neurol. 2019 Jan 25;10:23. doi: 10.3389/fneur.2019.00023. eCollection 2019.
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A Contemporary Perspective on the Management of Post-Craniotomy Headache and Pain.当代视角下的开颅术后头痛与疼痛管理
Curr Pain Headache Rep. 2018 Aug 14;22(10):69. doi: 10.1007/s11916-018-0722-4.