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一名无心脏病的儿科患者在长时间输注右美托咪定停药后出现室上性心动过速。

Supraventricular tachycardia after withdrawal of prolonged dexmedetomidine infusion in a paediatric patient without heart disease.

作者信息

Flores-González J Carlos, Estalella-Mendoza Ana, Lechuga-Sancho Alfonso M, Hernández-González Arturo, Rubio-Quiñones Fernando, Rodríguez-Campoy Patricia, Saldaña-Valderas Mónica

机构信息

Pediatric Intensivist, Pediatric Intensive Care Unit, Puerta del Mar University Hospital, Cádiz, Spain.

Pediatrics, Mother and Child Health, and Radiology Department, Cádiz University, Cádiz, Spain.

出版信息

J Clin Pharm Ther. 2017 Oct;42(5):653-655. doi: 10.1111/jcpt.12564. Epub 2017 May 27.

DOI:10.1111/jcpt.12564
PMID:28556301
Abstract

WHAT IS KNOWN AND OBJECTIVE

Dexmedetomidine (DEX) has been reported to be safe in paediatric patients.

CASE DESCRIPTION

We present the case of a girl without heart disease admitted at our PICU due to an influenza A acute respiratory distress syndrome, who suffered a paroxysmal supraventricular tachycardia (PSVT) twelve hours after DEX progressive withdrawal was completed.

WHAT IS NEW AND CONCLUSION

This is the first report of PSVT as an adverse reaction to DEX in a paediatric patient without heart disease.

摘要

已知信息与目的

据报道,右美托咪定(DEX)在儿科患者中是安全的。

病例描述

我们报告一例因甲型流感急性呼吸窘迫综合征入住我院儿科重症监护病房(PICU)的无心脏病女孩病例,该女孩在完成DEX逐渐撤药12小时后发生阵发性室上性心动过速(PSVT)。

新发现与结论

这是首例关于无心脏病儿科患者发生PSVT作为DEX不良反应的报告。

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Supraventricular tachycardia after withdrawal of prolonged dexmedetomidine infusion in a paediatric patient without heart disease.一名无心脏病的儿科患者在长时间输注右美托咪定停药后出现室上性心动过速。
J Clin Pharm Ther. 2017 Oct;42(5):653-655. doi: 10.1111/jcpt.12564. Epub 2017 May 27.
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引用本文的文献

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Clonidine for the Treatment of Agitation After Dexmedetomidine Discontinuation in Pediatric Patients: A Retrospective Cohort Study.可乐定用于治疗小儿患者右美托咪定停药后躁动:一项回顾性队列研究
J Pediatr Pharmacol Ther. 2021;26(8):821-827. doi: 10.5863/1551-6776-26.8.821. Epub 2021 Nov 10.
2
Dexmedetomidine: What's New for Pediatrics? A Narrative Review.右美托咪定:儿科领域有哪些新进展?一篇叙述性综述。
J Clin Med. 2020 Aug 24;9(9):2724. doi: 10.3390/jcm9092724.