Patel Rupa R, Mena Leandro, Nunn Amy, McBride Timothy, Harrison Laura C, Oldenburg Catherine E, Liu Jingxia, Mayer Kenneth H, Chan Philip A
Division of Infectious Diseases, Washington University in St. Louis, St. Louis, Missouri, United States of America.
Division of Infectious Diseases, University of Mississippi Medical Center, Jackson, Mississippi, United States of America.
PLoS One. 2017 May 30;12(5):e0178737. doi: 10.1371/journal.pone.0178737. eCollection 2017.
Pre-exposure prophylaxis (PrEP) can reduce U.S. HIV incidence. We assessed insurance coverage and its association with PrEP utilization. We reviewed patient data at three PrEP clinics (Jackson, Mississippi; St. Louis, Missouri; Providence, Rhode Island) from 2014-2015. The outcome, PrEP utilization, was defined as patient PrEP use at three months. Multivariable logistic regression was performed to determine the association between insurance coverage and PrEP utilization. Of 201 patients (Jackson: 34%; St. Louis: 28%; Providence: 28%), 91% were male, 51% were White, median age was 29 years, and 21% were uninsured; 82% of patients reported taking PrEP at three months. Insurance coverage was significantly associated with PrEP utilization. After adjusting for Medicaid-expansion and individual socio-demographics, insured patients were four times as likely to use PrEP services compared to the uninsured (OR: 4.49, 95% CI: 1.68-12.01; p = 0.003). Disparities in insurance coverage are important considerations in implementation programs and may impede PrEP utilization.
暴露前预防(PrEP)可降低美国的艾滋病毒发病率。我们评估了保险覆盖情况及其与PrEP使用的关联。我们回顾了2014年至2015年期间三家PrEP诊所(密西西比州杰克逊市;密苏里州圣路易斯市;罗德岛州普罗维登斯市)的患者数据。结果指标PrEP使用情况定义为患者在三个月时使用PrEP。进行多变量逻辑回归以确定保险覆盖情况与PrEP使用之间的关联。在201名患者中(杰克逊市:34%;圣路易斯市:28%;普罗维登斯市:28%),91%为男性,51%为白人,年龄中位数为29岁,21%未参保;82%的患者报告在三个月时服用了PrEP。保险覆盖情况与PrEP使用显著相关。在对医疗补助扩大和个体社会人口统计学因素进行调整后,参保患者使用PrEP服务的可能性是未参保患者的四倍(比值比:4.49,95%置信区间:1.68 - 12.01;p = 0.003)。保险覆盖方面的差异是实施项目中的重要考虑因素,可能会阻碍PrEP的使用。