Matalliotakis Michail, Goulielmos George N, Matalliotaki Charoula, Trivli Alexandra, Matalliotakis Ioannis, Arici Aydin
Department of Obstetrics and Gynecology, Venizeleio and Pananio General Hospital of Heraklion, Crete, Greece; Section of Molecular Pathology and Human Genetics Department of Internal Medicine, School of Medicine University of Crete, Crete, Greece.
Section of Molecular Pathology and Human Genetics Department of Internal Medicine, School of Medicine University of Crete, Crete, Greece.
J Pediatr Adolesc Gynecol. 2017 Oct;30(5):568-570. doi: 10.1016/j.jpag.2017.05.007. Epub 2017 May 27.
The aim of this retrospective study was to evaluate endometriosis in adolescent and young girls and further to review the menstrual, reproductive characteristics, and risk factors.
We reviewed the medical records of adolescent and young girls with endometriosis from 2 different countries. Data were collected and analyzed from charts of 900 patients with endometriosis.
Fifty-five female adolescents aged between 13 and 21 years (mean age 18.3 years) participated in our series. This study was conducted in the Obstetric and Gynecology Department of Venizeleio General Hospital of Crete and involved all patients diagnosed with endometriosis between 1996 and 2016.
Statistical methods included χ and Mann-Whitney U test.
Of 900 patients with endometriosis we found 55 female adolescents (6.1%). The mean age was 18.3 ± 2.3 years, significantly younger compared with the advanced endometriosis patients (32.7 ± 7.2; P < .001). Regarding the menstrual reproductive and others characteristics, we observed several differences in adolescent young girls compared with the advanced age endometriosis group. The factors associated with an increased risk for young women include age at menarche, dysmenorrhea, history of asthma, and a positive family history of endometriosis. Additionally, we report on 16 of 55 (32%) adolescent women with endometriosis and congenital malformations (P < .01) and 5 patients who were diagnosed with dry eye syndrome.
There is an association between endometriosis in adolescent and young women and risk factors including early menarche, early onset of dysmenorrhea, history of asthma, previous surgical procedures, obstructive genital anomalies, and family history of endometriosis.
这项回顾性研究的目的是评估青少年和年轻女性的子宫内膜异位症，并进一步回顾其月经、生殖特征及危险因素。
我们回顾了来自2个不同国家的患有子宫内膜异位症的青少年和年轻女性的病历。从900例子宫内膜异位症患者的病历中收集并分析数据。
55名年龄在13至21岁之间（平均年龄18.3岁）的女性青少年参与了我们的研究系列。本研究在克里特岛维尼泽利奥综合医院妇产科进行，纳入了1996年至2016年间所有诊断为子宫内膜异位症的患者。
统计方法包括χ检验和曼-惠特尼U检验。
在900例子宫内膜异位症患者中，我们发现了55名女性青少年（6.1%）。平均年龄为18.3±2.3岁，与晚期子宫内膜异位症患者相比明显更年轻（32.7±7.2岁；P<0.001）。关于月经、生殖及其他特征，我们观察到青少年年轻女性与高龄子宫内膜异位症组存在一些差异。与年轻女性风险增加相关的因素包括初潮年龄、痛经、哮喘病史以及子宫内膜异位症家族史阳性。此外，我们报告了55例子宫内膜异位症青少年女性中有16例（32%）合并先天性畸形（P<0.01），以及5例被诊断为干眼症的患者。
青少年和年轻女性的子宫内膜异位症与包括初潮早、痛经早发、哮喘病史、既往手术史、生殖器梗阻性畸形以及子宫内膜异位症家族史等危险因素之间存在关联。
