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带血管腓骨或诱导膜治疗先天性胫骨假关节:18例患者平均9.5年随访的多中心研究

Vascularised fibula or induced membrane to treat congenital pseudarthrosis of the Tibia: A multicentre study of 18 patients with a mean 9.5-year follow-up.

作者信息

Vigouroux F, Mezzadri G, Parot R, Gazarian A, Pannier S, Chotel F

机构信息

Service de chirurgie orthopédique pédiatrique, hôpital Femme-Mère-Enfant, Bron, France.

Service de chirurgie orthopédique pédiatrique, hôpital Femme-Mère-Enfant, Bron, France.

出版信息

Orthop Traumatol Surg Res. 2017 Sep;103(5):747-753. doi: 10.1016/j.otsr.2017.05.005. Epub 2017 May 27.

DOI:10.1016/j.otsr.2017.05.005
PMID:28559144
Abstract

BACKGROUND

The objective of this study was to compare outcomes of two surgical techniques used to treat congenital pseudarthrosis of the tibia (CPT), the induced membrane technique (IM) and the transfer of the contralateral vascularised fibula (VF).

HYPOTHESIS

The IM technique produces similar outcomes to those of VF grafting in terms of healing and function, while being simpler and having a lower complication rate.

MATERIAL AND METHOD

This retrospective multicentre study included 18 patients with a mean age of 2.8 years at surgery. Among them, 11 had neurofibromatosis type 1 (NF1). The IM technique was used in 10 patients and VF grafting in 8 patients. Mean follow-up was 9.5 years (range: 5-15 years).

RESULTS

The two groups showed no significant differences for healing or the occurrence of complications such as limb length discrepancy and residual malalignment. Two patients required amputation, one in each group. The mean number of surgical procedures per patient was 4.7 in the IM group and 5 in the VF group.

DISCUSSION

Outcomes are similar with the two techniques. Although VF grafting theoretically involves a single stage, the mean number of surgical procedures was not lower than after the IM technique. The IM technique was associated with lower risks of complications and residual donor site abnormalities. Regardless of the reconstruction technique, the quality of the initial bone resection and internal fixation, particularly regarding alignment, is of the utmost importance.

LEVEL OF EVIDENCE

IV, comparative retrospective study.

摘要

背景

本研究的目的是比较两种用于治疗先天性胫骨假关节(CPT)的手术技术的疗效,即诱导膜技术(IM)和对侧带血管腓骨转移术(VF)。

假设

IM技术在愈合和功能方面产生的结果与VF移植术相似,同时更简单且并发症发生率更低。

材料与方法

这项回顾性多中心研究纳入了18例手术时平均年龄为2.8岁的患者。其中,11例患有1型神经纤维瘤病(NF1)。10例患者采用IM技术,8例患者采用VF移植术。平均随访时间为9.5年(范围:5 - 15年)。

结果

两组在愈合或并发症(如肢体长度差异和残余畸形)的发生方面无显著差异。两名患者需要截肢,每组各一名。IM组每位患者的平均手术次数为4.7次,VF组为5次。

讨论

两种技术的结果相似。尽管VF移植术理论上是一期手术,但平均手术次数并不低于IM技术术后的次数。IM技术的并发症风险和供区残余异常风险较低。无论采用何种重建技术,初始骨切除和内固定的质量,尤其是在对线方面,至关重要。

证据级别

IV,比较性回顾性研究。

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