Vouga Manon, Baud David, Greub Gilbert
Center for Research on Intracellular Bacteria, Institute of Microbiology, Faculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.
Materno-fetal and Obstetrics Research Unit, Department Femme-mère-enfant, Maternity, University Hospital, Lausanne, Switzerland.
Antimicrob Agents Chemother. 2017 Jul 25;61(8). doi: 10.1128/AAC.00638-17. Print 2017 Aug.
In past years, several -related bacteria have been discovered, including , the founding member of the family. We evaluated the antimicrobial susceptibility patterns of this emerging intracellular bacterium and highlighted significant differences, compared with related members. was susceptible to macrolides, clindamycin, cyclines, rifampin, and quinolones. Importantly, unlike other members, treatment with β-lactams and vancomycin did not induce the formation of aberrant bodies, leading to a completely resistant phenotype.
在过去几年中，已经发现了几种相关细菌，包括该菌属的创始成员。我们评估了这种新出现的细胞内细菌的抗菌药敏模式，并强调了与相关菌属成员相比的显著差异。该菌对大环内酯类、克林霉素、四环素类、利福平及喹诺酮类敏感。重要的是，与其他菌属成员不同，用β-内酰胺类和万古霉素治疗不会诱导异常菌体的形成，从而导致完全耐药表型。
