Oray Merih, Cebeci Zafer, Kir Nur, Turgut Ozturk Banu, Oksuz Lutfiye, Tugal-Tutkun Ilknur
Istanbul University, Istanbul Faculty of Medicine, Department of Ophthalmology, Istanbul, Turkey.
Selcuk University Faculty of Medicine, Department of Ophthalmology, Konya, Turkey.
Saudi J Ophthalmol. 2017 Apr-Jun;31(2):106-108. doi: 10.1016/j.sjopt.2017.03.002. Epub 2017 Mar 12.
Brucellosis may be associated with a wide range of ophthalmic manifestations including endophthalmitis, which is a sight-threatening condition that needs to be rapidly recognized and treated to avoid permanent visual loss A 26-year-old female with a 6-month history of vision loss in the left eye was treated with high dose systemic corticosteroids and azathioprine with an initial misdiagnosis elsewhere. A dense vitreous haze with opacities at the posterior hyaloid and a wide area of retinochoroiditis led to the diagnosis of endogenous endophthalmitis at presentation to us. The vitreous sample and blood cultures demonstrated growth of She received 6 months of systemic antibiotherapy, which resulted in resolution of inflammation; however, visual acuity remained poor due to irreversible damage. Infectious etiology, including brucellosis in endemic countries, has to be considered in the differential diagnosis before administering immunomodulatory therapy in patients with panuveitis of unknown origin.
布鲁氏菌病可能与多种眼部表现相关，包括眼内炎，这是一种威胁视力的疾病，需要迅速识别并治疗以避免永久性视力丧失。一名26岁女性，有6个月左眼视力丧失病史，最初在其他地方被误诊，接受了高剂量全身皮质类固醇和硫唑嘌呤治疗。就诊时，浓密的玻璃体混浊伴后玻璃体膜混浊以及广泛的视网膜脉络膜炎导致诊断为内源性眼内炎。玻璃体样本和血培养显示生长。她接受了6个月的全身抗微生物治疗，炎症得以消退；然而，由于不可逆转的损伤，视力仍然很差。在对不明原因的全葡萄膜炎患者进行免疫调节治疗之前，鉴别诊断时必须考虑包括布鲁氏菌病在内的感染性病因，尤其是在流行国家。
