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眼内髓上皮瘤伪装成永存原始玻璃体增生症和全眼球炎:诊断难题

Intra-ocular medulloepithelioma as a masquerade for PHPV and Panophthalmitis: a Diagnostic Dilemma.

作者信息

Pushker Neelam, Bajaj Mandeep S, Singh Ashutosh K, Lokdarshi Gautam, Bakhshi Sameer, Kashyap Seema

机构信息

Oculoplastic and Pediatric Ophthalmology Services, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

Paediatric Oncology, Dr. B.R.A. IRCH, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

出版信息

Saudi J Ophthalmol. 2017 Apr-Jun;31(2):109-111. doi: 10.1016/j.sjopt.2017.02.004. Epub 2017 Feb 21.

DOI:10.1016/j.sjopt.2017.02.004
PMID:28559724
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5436372/
Abstract

A previously diagnosed child of persistent hyperplastic primary vitreous (PHPV) with painless blind eye remained clinically silent for about 3 years follow-up. The child suddenly presented as a case of orbital cellulitis and panopthalmitis with meningitis. No definite mass lesion was detected on ultrasonography, magnetic resonance imaging (MRI) and positron emission tomography (PET) scan. Histopathology of the enucleated eye revealed intra-ocular medulloepithelioma as the culprit of sterile panophthalmitis and orbital inflammation.

摘要

一名先前被诊断为持续性增生性原发性玻璃体(PHPV)的儿童,患眼无痛且失明,在约3年的随访期内临床症状无变化。该儿童突然出现眼眶蜂窝织炎、全眼球炎并伴有脑膜炎的症状。超声检查、磁共振成像(MRI)和正电子发射断层扫描(PET)均未发现明确的肿块病变。摘除眼球的组织病理学检查显示,眼内髓上皮瘤是无菌性全眼球炎和眼眶炎症的病因。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/5436372/fefe5ed6dc0c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/5436372/8d158a4d2b8e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/5436372/fefe5ed6dc0c/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/5436372/8d158a4d2b8e/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a0ff/5436372/fefe5ed6dc0c/gr2.jpg

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本文引用的文献

1
Ciliary body medulloepithelioma: analysis of 41 cases.睫状体髓上皮瘤:41 例分析。
Ophthalmology. 2013 Dec;120(12):2552-2559. doi: 10.1016/j.ophtha.2013.05.015. Epub 2013 Jun 21.
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Malignant teratoid medulloepithelioma with retinoblastic and rhabdomyoblastic differentiation.
J AAPOS. 2013 Jun;17(3):328-31. doi: 10.1016/j.jaapos.2013.02.005.
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Retinoblastoma presenting with orbital cellulitis.以眼眶蜂窝织炎为表现的视网膜母细胞瘤。
J AAPOS. 2013 Jun;17(3):282-6. doi: 10.1016/j.jaapos.2013.02.009.
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Retinoblastoma associated orbital cellulitis.视网膜母细胞瘤相关性眼眶蜂窝织炎
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