Dindia L A, Alderman S L, Gillis T E
Department of Integrative Biology, University of Guelph, Guelph, Ontario, Canada.
Data Brief. 2017 May 10;13:32-36. doi: 10.1016/j.dib.2017.05.016. eCollection 2017 Aug.
This data article presents the first description of the rainbow trout cardiac ventricle at the level of the proteome, with more than 700 proteins identified and quantified using isobaric tags for relative and absolute quantitation (iTRAQ) and LC-MS/MS. The abundances of these proteins were compared across 4 durations of moderate exercise training (0, 4, 7, and 14 d), and a total of 107 proteins were differentially abundant during the course of the training program. The differentially abundant proteins are presented here grouped by functional classification. In the research article associated with this data [1], the temporal changes in the cardiac proteome are discussed in the context of cardiac remodelling and development of a trained heart phenotype.
本数据文章首次在蛋白质组水平对虹鳟鱼的心室进行了描述，使用等压标签相对和绝对定量（iTRAQ）及液相色谱-串联质谱（LC-MS/MS）鉴定并定量了700多种蛋白质。比较了这些蛋白质在4个中等强度运动训练阶段（0、4、7和14天）的丰度，在整个训练过程中共有107种蛋白质丰度存在差异。此处按功能分类展示了这些差异丰度蛋白质。在与本数据相关的研究文章[1]中，在心脏重塑和训练有素的心脏表型发育的背景下讨论了心脏蛋白质组的时间变化。
