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急性淋巴细胞白血病治疗期间粒细胞吞噬活性的研究。

The study of phagocytic activity of granulocytes during the treatment of acute lymphoblastic leukemia.

作者信息

Bogusławska-Jaworska J, Pisarek J, Szymaniec S

出版信息

Arch Immunol Ther Exp (Warsz). 1978;26(1-6):851-4.

PMID:285644
Abstract

The phagocytic function of granulocytes from peripheral blood of 14 children with ALL before and during therapy was studied. The children were treated according Pinkel's Protocol VIII. Peripheral blood granulocytes were evaluated for their phagocytic activity by tube phagocytosis test with Staphylococcus aureus. The transient decrease of phagocytic activity after cranial irradiation was noted. This impairment was coupled with increased incidence of infections.

摘要

对14名急性淋巴细胞白血病(ALL)患儿治疗前及治疗期间外周血粒细胞的吞噬功能进行了研究。这些患儿按照平克尔方案VIII进行治疗。通过用金黄色葡萄球菌进行试管吞噬试验,对外周血粒细胞的吞噬活性进行评估。注意到颅脑照射后吞噬活性出现短暂下降。这种损害与感染发生率增加相关。

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