合成促吞噬肽及其类似物对急性淋巴细胞白血病患儿粒细胞功能的影响。
The influence of synthetic tuftsin and its analogs on the function of granulocytes of children with acute lymphoblastic leukemia.
作者信息
Kazanowska B, Steuden W, Bogusławska-Jaworska J, Konopińska D
机构信息
Department of Children's Haematology, Medical Academy, Wrocław.
出版信息
Arch Immunol Ther Exp (Warsz). 1987;35(2):169-73.
PMID:3482149
Abstract
The effect of tuftsin, its synthetic analogs and arginine on phagocytosis of Staphylococcus aureus by granulocytes from leukemic children was investigated in vitro. The high stimulatory effect of tuftsin and arginine was shown. The decrease of phagocytosis of PMN from healthy subjects after preincubation with its analogs and arginine was observed, suggesting the regulatory effect of these peptides.
摘要
在体外研究了促吞噬素、其合成类似物和精氨酸对白血病儿童粒细胞吞噬金黄色葡萄球菌的影响。结果显示促吞噬素和精氨酸具有较高的刺激作用。观察到健康受试者的中性粒细胞在与促吞噬素类似物和精氨酸预孵育后吞噬作用降低，提示这些肽具有调节作用。
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