DeCandido P, Reinig J W, Dwyer A J, Thompson K J, Ducker T B
Anne Arundel MRI, Annapolis, MD 21401.
J Spinal Disord. 1988;1(1):9-15.
The lumbar spine magnetic resonance (MR) studies in 246 consecutive patients who suffered from persistent back and leg pain were evaluated for the degree of degenerative disc disease and the presence of disc bulging, prolapse, or herniation. No patient had a history of previous back surgery. In those patients, degenerative disc changes increased with age until the fifth decade of life, after which a relatively similar proportion of patients had degenerative disc disease. Significant dehydration and degeneration occurred in less than 5% of the upper two disc spaces while L4/5 and L5/S1 had marked changes in greater than 20%. Prolapse and herniation progressively increased with each lower interspace, where at L5/S1 it was present in nearly one-third of the patients. Although a few patients had disc prolapse or herniation with a nondegenerated disc, there was a relationship between the presence of disc degeneration and prolapse or herniation.
对246例持续存在腰腿痛的连续患者进行腰椎磁共振（MR）研究，评估椎间盘退变程度以及椎间盘膨出、脱垂或突出的情况。所有患者均无既往背部手术史。在这些患者中，椎间盘退变变化随年龄增长，直至生命的第五个十年，此后患椎间盘退变疾病的患者比例相对相似。上两个椎间盘间隙中不到5%发生明显脱水和退变，而L4/5和L5/S1间隙退变明显的比例大于20%。脱垂和突出随每个更低的间隙逐渐增加，在L5/S1间隙近三分之一的患者中存在。虽然少数患者有无退变椎间盘的椎间盘脱垂或突出，但椎间盘退变与脱垂或突出之间存在关联。
