Garagiola U, Dacatra U, Braconaro F, Porretti E, Pisetti A, Azzolini V
Ciba-Geigy S.p.A., Medical Department, Origgio (VA), Italy.
Clin Ther. 1988;10(5):553-8.
A double-blind study was designed to compare the efficacy and tolerability of pirprofen and lysine soluble aspirin administered by iontophoresis to 80 patients with various painful rheumatic diseases. Treatment lasted two weeks, with five administrations a week, each lasting 20 minutes (direct current; mean intensity, 2.3 mA). After five administrations, patients showed significant improvement in pain at rest and on movement, with no significant differences between pirprofen and aspirin. Final results were excellent or good in about 75% of the patients treated and functional improvement was satisfactory in about 80%. There were no side effects.
一项双盲研究旨在比较离子导入法给予吡洛芬和赖氨酸阿司匹林对80例患有各种疼痛性风湿性疾病患者的疗效和耐受性。治疗持续两周，每周给药五次，每次持续20分钟（直流电；平均强度，2.3毫安）。五次给药后，患者静息和活动时的疼痛有显著改善，吡洛芬和阿司匹林之间无显著差异。约75%接受治疗的患者最终结果为优或良，约80%的患者功能改善令人满意。未出现副作用。
