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Syntax评分在接受经皮冠状动脉介入治疗或冠状动脉旁路移植术的慢性冠状动脉疾病患者中的预测价值:一项初步研究。

The Predictive Value of the Syntax Score in Patients With Chronic Coronary Artery Disease Undergoing Percutaneous Coronary Intervention or Coronary Artery Bypass Grafting: A Pilot Study.

作者信息

Papadopoulos K, Lekakis I, Nicolaides E

机构信息

Cardiology Department, Medical Check-up Centre, 21 Costa Anaxagora Street, 2014, Nicosia, Cyprus.

Cardiology Department, Attikon University Hospital, Rimini 1, Chaidari 124 62, Athens, Greece.

出版信息

Open Cardiovasc Med J. 2017 Apr 17;11:28-32. doi: 10.2174/1874192401711010028. eCollection 2017.

DOI:10.2174/1874192401711010028
PMID:28567131
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5418927/
Abstract

OBJECTIVES

To evaluate the usefulness of the SYNTAX score (SS) in predicting 1-year clinical outcomes in a population of patients with chronic coronary artery disease (CAD) undergoing percutaneous coronary intervention (PCI) or coronary artery bypass grafting (CABG).

BACKGROUND

Despite the proven prognostic value of the SS in patients with multivessel and/or left main (LM) CAD, its usefulness in other patient subsets remains uncertain.

METHODS

This was a prospective single centre cohort study conducted from September 2012 to November 2014 at the Nicosia General Hospital, Cyprus. Patients (n=140 94% men and 6% women) with chronic CAD undergoing revascularization with either PCI or CABG were evaluated.

RESULTS

At 1-year, angina occurred in 20 patients (14.3%), myocardial infarction (MI) in 3 patients (2.1%), repeat revascularization procedures in 9 patients (6.4%) and death in 12 patients (8.6%). The SS independently predicted angina (p=0.024) but was not predictive of MI (p=0.964), death (p=0.292) or repeat revascularization (p=0.069).

CONCLUSION

In this patient population, the SS predicted angina in the year following revascularization but was not predictive of MI, death or repeat revascularization.

摘要

目的

评估SYNTAX评分(SS)对接受经皮冠状动脉介入治疗(PCI)或冠状动脉旁路移植术(CABG)的慢性冠状动脉疾病(CAD)患者1年临床结局的预测价值。

背景

尽管SS在多支血管和/或左主干(LM)CAD患者中已被证实具有预后价值,但其在其他患者亚组中的效用仍不确定。

方法

这是一项前瞻性单中心队列研究,于2012年9月至2014年11月在塞浦路斯尼科西亚综合医院进行。对接受PCI或CABG血运重建的慢性CAD患者(n = 140,男性94%,女性6%)进行评估。

结果

1年时,20例患者(14.3%)发生心绞痛,3例患者(2.1%)发生心肌梗死(MI),9例患者(6.4%)进行了再次血运重建手术,12例患者(8.6%)死亡。SS独立预测心绞痛(p = 0.024),但不能预测MI(p = 0.964)、死亡(p = 0.292)或再次血运重建(p = 0.069)。

结论

在该患者群体中,SS可预测血运重建术后1年内心绞痛的发生,但不能预测MI、死亡或再次血运重建。

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本文引用的文献

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Lancet. 2013 Feb 23;381(9867):629-38. doi: 10.1016/S0140-6736(13)60141-5.
2
Strategies for multivessel revascularization in patients with diabetes.多血管血运重建策略在糖尿病患者中的应用。
N Engl J Med. 2012 Dec 20;367(25):2375-84. doi: 10.1056/NEJMoa1211585. Epub 2012 Nov 4.
3
Comparison of long-term outcome after percutaneous coronary intervention versus coronary artery bypass grafting in patients with unprotected left main coronary artery disease (from the CREDO-Kyoto PCI/CABG Registry Cohort-2).比较经皮冠状动脉介入治疗与冠状动脉旁路移植术治疗无保护左主干冠状动脉疾病患者的长期预后(来自 CREDO-Kyoto PCI/CABG 注册研究队列-2)。
Am J Cardiol. 2012 Oct 1;110(7):924-32. doi: 10.1016/j.amjcard.2012.05.022. Epub 2012 Jun 19.
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J Am Coll Cardiol. 2011 Jun 14;57(24):2389-97. doi: 10.1016/j.jacc.2011.02.032.
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