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Malignization of a vestibular schwannoma 13 years after radiation therapy.

作者信息

Simmermacher S, Vordermark D, Kegel T, Strauss C

机构信息

Klinik für Neurochirurgie, University Hospital Halle, Ernst-Grube-Straße 40, 06120, Halle, Germany.

Klinik für Strahlentherapie, University Hospital Halle, Halle, Germany.

出版信息

HNO. 2017 Aug;65(Suppl 2):153-157. doi: 10.1007/s00106-017-0362-8.

DOI:10.1007/s00106-017-0362-8
PMID:28567476
Abstract

This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.

摘要

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Malignization of a vestibular schwannoma 13 years after radiation therapy.
HNO. 2017 Aug;65(Suppl 2):153-157. doi: 10.1007/s00106-017-0362-8.
2
[Malignization of vestibular schwannoma 13 years after radiation therapy].
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本文引用的文献

1
Management and prognosis of malignant peripheral nerve sheath tumors: The experience of the French Sarcoma Group (GSF-GETO).恶性外周神经鞘瘤的管理与预后：法国肉瘤研究组（GSF-GETO）的经验
Eur J Cancer. 2016 Mar;56:77-84. doi: 10.1016/j.ejca.2015.12.015. Epub 2016 Jan 26.
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Late malignant transformation of vestibular schwannoma in the absence of irradiation: case report.前庭神经鞘瘤在未接受放疗的情况下恶变：病例报告。
J Neurosurg. 2016 Aug;125(2):372-7. doi: 10.3171/2015.6.JNS1544. Epub 2015 Nov 27.
3
Evaluation of Reported Malignant Transformation of Vestibular Schwannoma: De Novo and After Stereotactic Radiosurgery or Surgery.
前庭神经鞘瘤报告的恶性转化评估：新发及立体定向放射外科手术或手术后情况
Otol Neurotol. 2015 Sep;36(8):1301-8. doi: 10.1097/MAO.0000000000000801.
4
The Changing Landscape of Vestibular Schwannoma Management in the United States--A Shift Toward Conservatism.美国前庭神经鞘瘤治疗格局的变化——向保守主义的转变。
Otolaryngol Head Neck Surg. 2015 Sep;153(3):440-6. doi: 10.1177/0194599815590105. Epub 2015 Jun 30.
5
Long-term outcome after highly advanced single-dose or fractionated radiotherapy in patients with vestibular schwannomas - pooled results from 3 large German centers.大剂量单次或分割放疗治疗前庭神经鞘瘤患者的长期疗效 - 来自 3 个德国大型中心的汇总结果。
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6
What is the risk of malignant transformation of vestibular schwannoma following radiosurgery?放射外科治疗后前庭神经鞘瘤发生恶性转化的风险是多少？
Laryngoscope. 2015 Aug;125(8):1761-2. doi: 10.1002/lary.25164. Epub 2015 Feb 13.
7
Malignant transformation in vestibular schwannoma: report of a single case, literature search, and debate.前庭神经鞘瘤的恶性转化：一例报告、文献检索及讨论
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8
Fractionated stereotactic radiotherapy for acoustic neuromas: long-term outcomes.分次立体定向放射治疗听神经瘤：长期结果。
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9
[Imaging of acoustic neuroma (vestibular schwannoma). Breakthrough or dilemma?].[听神经瘤（前庭神经鞘瘤）的影像学：突破还是困境？]
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