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[Malignization of vestibular schwannoma 13 years after radiation therapy].

作者信息

Simmermacher S, Vordermark D, Kegel T, Strauss C

机构信息

Universitätsklinik und Poliklinik für Neurochirurgie, Universitätsklinikum Halle (Saale), Ernst-Grube-Straße 40, 06120, Halle (Saale), Deutschland.

Klinik für Strahlentherapie, Universitätsklinikum Halle, Halle (Saale), Deutschland.

出版信息

HNO. 2017 Sep;65(9):766-770. doi: 10.1007/s00106-016-0321-9.

DOI:10.1007/s00106-016-0321-9
PMID:28058466
Abstract

This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.

摘要

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本文引用的文献

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Eur J Cancer. 2016 Mar;56:77-84. doi: 10.1016/j.ejca.2015.12.015. Epub 2016 Jan 26.
2
Late malignant transformation of vestibular schwannoma in the absence of irradiation: case report.前庭神经鞘瘤在未接受放疗的情况下恶变：病例报告。
J Neurosurg. 2016 Aug;125(2):372-7. doi: 10.3171/2015.6.JNS1544. Epub 2015 Nov 27.
3
Evaluation of Reported Malignant Transformation of Vestibular Schwannoma: De Novo and After Stereotactic Radiosurgery or Surgery.
听神经瘤经放射外科手术后转变为H3K27三甲基化缺失的恶性外周神经鞘瘤——病例报告及文献复习
Neurosurg Rev. 2022 Feb;45(1):915-922. doi: 10.1007/s10143-021-01620-3. Epub 2021 Aug 15.
4
Intralabyrinthine schwannomas : Surgical management and hearing rehabilitation with cochlear implants.迷路内神经鞘瘤：手术治疗及人工耳蜗听力康复
HNO. 2017 Aug;65(Suppl 2):136-148. doi: 10.1007/s00106-017-0364-6.
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[Intralabyrinthine schwannomas : Surgical management and hearing rehabilitation with cochlear implants. German version].[迷路内神经鞘瘤：手术治疗与人工耳蜗听力康复。德文版]
HNO. 2017 May;65(5):419-433. doi: 10.1007/s00106-017-0361-9.
前庭神经鞘瘤报告的恶性转化评估：新发及立体定向放射外科手术或手术后情况
Otol Neurotol. 2015 Sep;36(8):1301-8. doi: 10.1097/MAO.0000000000000801.
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Otolaryngol Head Neck Surg. 2015 Sep;153(3):440-6. doi: 10.1177/0194599815590105. Epub 2015 Jun 30.
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