Simmermacher S, Vordermark D, Kegel T, Strauss C
Universitätsklinik und Poliklinik für Neurochirurgie, Universitätsklinikum Halle (Saale), Ernst-Grube-Straße 40, 06120, Halle (Saale), Deutschland.
Klinik für Strahlentherapie, Universitätsklinikum Halle, Halle (Saale), Deutschland.
HNO. 2017 Sep;65(9):766-770. doi: 10.1007/s00106-016-0321-9.
This article presents a case of malignant transformation of vestibular schwannoma 13 years after stereotactic radiation therapy, which lead to an acute life-threatening condition. Although the observation is currently only based on case reports, an increasing number of these support the hypothesis that there is a relevant risk of malignant transformation in the long-term course of previously irradiated vestibular schwannomas. Therefore, long-term MRI follow-up should be considered.