J Hypertens Suppl. 1985 Dec;3(3):S513-8.
The International Prospective Primary Prevention Study in Hypertension (IPPPSH) was a long-term clinical trial designed to examine the effects of treatment on hypertension. It shows that in a population who at entry to the study had diastolic blood pressures of 100-125 mmHg, failure to achieve blood pressure control increases the risk of sudden death and myocardial infarction as well as stroke in both sexes and emphasizes the need to control blood pressure on a long-term basis. The absolute cardiac risk reduction associated with pressure control is greater for men than women below achieved diastolic pressures of 101-105 mmHg.
国际高血压前瞻性初级预防研究（IPPPSH）是一项旨在研究高血压治疗效果的长期临床试验。该研究表明，在研究开始时舒张压为100 - 125 mmHg的人群中，未能实现血压控制会增加男女猝死、心肌梗死以及中风的风险，并强调了长期控制血压的必要性。在舒张压达到101 - 105 mmHg以下时，与血压控制相关的绝对心脏风险降低对男性的作用大于女性。
