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偏头痛发作与口服避孕药引起的血小板聚集性增加。

Migraine attacks and increased platelet aggregability induced by oral contraceptives.

作者信息

Mazal S

出版信息

Aust N Z J Med. 1978 Dec;8(6):646-8. doi: 10.1111/j.1445-5994.1978.tb04856.x.

DOI:10.1111/j.1445-5994.1978.tb04856.x
PMID:285686
Abstract

A case where common and complicated migraine attacks appeared during the course of oral contraception is reported. The attacks of complicated migraine also continued to appear after the contraceptives were stopped. Increased platelet aggregability was found at the time when the complicated migraine attacks were frequent and, therefore, treatment with dipyridamole and aspirin was given. At the time when a gradual reduction of the platelet aggregability was observed, a decrease in the frequency, and eventual disappearance of the complicated migraine attacks was simultaneously seen. Causal relationship between increased platelet aggregability and complicated migraine attacks is suggested.

摘要

报告了一例在口服避孕药期间出现普通型和复杂性偏头痛发作的病例。即使在停用避孕药后,复杂性偏头痛发作仍持续出现。在复杂性偏头痛发作频繁时发现血小板聚集性增加,因此给予双嘧达莫和阿司匹林治疗。当观察到血小板聚集性逐渐降低时,复杂性偏头痛发作的频率同时降低,最终消失。提示血小板聚集性增加与复杂性偏头痛发作之间存在因果关系。

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1
Migraine attacks and increased platelet aggregability induced by oral contraceptives.偏头痛发作与口服避孕药引起的血小板聚集性增加。
Aust N Z J Med. 1978 Dec;8(6):646-8. doi: 10.1111/j.1445-5994.1978.tb04856.x.
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J Neurol Neurosurg Psychiatry. 1977 Jan;40(1):9-10. doi: 10.1136/jnnp.40.1.9.
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Comparison of metabolic and clinical effects of four oral contraceptive formulations and a contraceptive vaginal ring.四种口服避孕药配方与一种避孕阴道环的代谢及临床效果比较。
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引用本文的文献

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Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC).激素避孕与偏头痛女性缺血性卒中风险:欧洲头痛联盟(EHF)和欧洲避孕与生殖健康学会(ESC)的共识声明
J Headache Pain. 2017 Oct 30;18(1):108. doi: 10.1186/s10194-017-0815-1.
2
The effect of an antiserotonin agent pizotifen on platelet aggregability in migraine patients.抗5-羟色胺药苯噻啶对偏头痛患者血小板聚集性的影响。
J Neurol Neurosurg Psychiatry. 1980 Dec;43(12):1137-40. doi: 10.1136/jnnp.43.12.1137.