癌症患者疼痛的药物管理
Drug management of pain in cancer patients.
作者信息
Tuttle C B
出版信息
Can Med Assoc J. 1985 Jan 15;132(2):121-34.
Abstract
Chronic severe cancer pain is often not well controlled because both patient and physician have a poor understanding of the nature of the pain and of the actions of various potent analgesics. Physicians often fail to tailor analgesic dosages to the needs of the individual and unnecessarily limit the dosage because they have an ill founded fear that the patient will become addicted. The basis of rational management of cancer pain with drugs is an appropriate analgesic given regularly in doses adequate to suppress pain continuously. This review compares the potent analgesics and identifies and discusses those that have a role in treating chronic cancer pain. It emphasizes the value of morphine sulfate and gives information on starting and individualizing dosages and managing side effects.
摘要
慢性重度癌痛往往控制不佳，因为患者和医生对疼痛的本质以及各种强效镇痛药的作用了解不足。医生常常未能根据个体需求调整镇痛药剂量，且不必要地限制剂量，因为他们毫无根据地担心患者会上瘾。合理使用药物治疗癌痛的基础是定期给予适当的镇痛药，剂量要足以持续抑制疼痛。本综述比较了强效镇痛药，识别并讨论了那些在治疗慢性癌痛中发挥作用的药物。它强调了硫酸吗啡的价值，并提供了起始剂量、个体化剂量以及处理副作用的相关信息。
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