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布基纳法索亚尔加杜·韦德拉奥果教学医院严重产前出血的发生率及结局

Incidence and outcome of severe ante-partum hemorrhage at the Teaching Hospital Yalgado Ouédraogo in Burkina Faso.

作者信息

Lankoande Martin, Bonkoungou Papougnezambo, Ouandaogo Sosthène, Dayamba Marcelin, Ouedraogo Ali, Veyckmans Francis, Ouédraogo Nazinigouba

机构信息

Resident Anesthesia and Resuscitation, Yalgado Ouedraogo Hospital, 15 BP 106, Ouagadougou 15, Burkina Faso.

Yalgado Ouédraogo Hospital, Ouagadougou, Burkina Faso.

出版信息

BMC Emerg Med. 2017 May 31;17(1):17. doi: 10.1186/s12873-017-0128-3.

Abstract

BACKGROUND

Hemorrhage is the main cause of maternal death during pregnancy. This study aims to evaluate incidence and outcomes of Severe Ante Partum Hemorrhage (SAPH) during the third trimester of pregnancy prior to delivery.

METHODS

Analytical cross-sectional study with prospective data collection during 12 months in Yalgado Ouedraogo Hospital, Ouagadougou, Burkina Faso. In this context SAPH is specifically referring to Ante Partum Hemorrhage (APH) and Intra Partum Hemorrhage (IPH) in the 3rd trimester. Postpartum Hemorrhage (PPH) was not included.

RESULTS

During our study 7,469 women were admitted in obstetrics and 122 cases of SAPH were recorded. SAPH represented 1.6% (n = 122) of hospitalizations causes and 14.5% (n = 1083) of hemorrhages during pregnancy. Mean age was 27.8 ± 6.9 years, mean parity 2.8 ± 1.3 and mean duration of pregnancy was 37 Weeks Amenorrhea (WA). Evacuation from other facilities was the main mode of admission (91.8%, n = 112) and blood transfusion was the essence of resuscitation. Complications were observed in 80.3% (n = 98). During the study, 118 maternal deaths were reported of which 15.6% (n = 19) related to SAPH. Among SAPH cases who died (n = 19) majority (n = 16) had severe anemia (n = 16; 82.6%, p = 0.004). Ten women (8.19%) were admitted in Intensive Care Unit (ICU). Fifteen premature births (12.3%) and 22 perinatal deaths (18.1%) were recorded. Evacuation (p = 0.04), critical clinical condition during admission (p = 0.004), and Uterine Rupture (UR) (p = 0.002) were associated with poor outcome. The Retroplacental Hemorrhage (RPH) (40.9%) was the most common cause of fetal death (p = 0.005) and was associated with High Blood Pressure (HBP) and pre-eclampsia.

CONCLUSION

APH is a complication associated with significant maternal and fetal morbidity and mortality.

摘要

背景

出血是孕期孕产妇死亡的主要原因。本研究旨在评估分娩前妊娠晚期严重产前出血(SAPH)的发生率及结局。

方法

在布基纳法索瓦加杜古的亚尔加杜·韦德拉奥戈医院进行了一项为期12个月的前瞻性数据收集的分析性横断面研究。在此研究中,SAPH具体指妊娠晚期的产前出血(APH)和产时出血(IPH)。不包括产后出血(PPH)。

结果

在我们的研究中,7469名妇女入住产科,记录到122例SAPH病例。SAPH占住院原因的1.6%(n = 122),占孕期出血的14.5%(n = 1083)。平均年龄为27.8±6.9岁,平均产次为2.8±1.3,平均妊娠时长为37周闭经(WA)。从其他医疗机构转诊是主要的入院方式(91.8%,n = 112),输血是复苏的关键。80.3%(n = 98)的患者出现了并发症。在研究期间,报告了118例孕产妇死亡,其中15.6%(n = 19)与SAPH有关。在死亡的SAPH病例中(n = 19),大多数(n = 16)患有严重贫血(n = 16;82.6%,p = 0.004)。10名妇女(8.19%)入住了重症监护病房(ICU)。记录到15例早产(12.3%)和22例围产儿死亡(18.1%)。转诊(p = 0.04)、入院时的危急临床状况(p = 0.004)和子宫破裂(UR)(p = 0.002)与不良结局相关。胎盘后出血(RPH)(40.9%)是胎儿死亡的最常见原因(p = 0.005),并与高血压(HBP)和先兆子痫相关。

结论

产前出血是一种与孕产妇和胎儿的高发病率及死亡率相关的并发症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ef63/5452328/2b171fe2f396/12873_2017_128_Fig1_HTML.jpg

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