Department of Surgery, Cantonal Hospital Olten, Olten, Switzerland.
Department of Visceral and Transplantation Surgery, University Hospital Zurich, Zurich, Switzerland.
Br J Surg. 2017 Aug;104(9):1141-1159. doi: 10.1002/bjs.10574. Epub 2017 Jun 1.
The purpose of this study was to evaluate improvements in cosmetic results and postoperative morbidity for single-incision laparoscopic cholecystectomy (SILC) in comparison with multiport laparoscopic cholecystectomy (MLC).
A literature search was undertaken for RCTs comparing SILC with MLC in adult patients with benign gallbladder disease. Primary outcomes were body image and cosmesis scores at different time points. Secondary outcomes included intraoperative and postoperative complications, postoperative pain and frequency of port-site hernia.
Thirty-seven RCTs were included, with a total of 3051 patients. The body image score favoured SILC at all time points (short term: mean difference (MD) -2·09, P < 0·001; mid term: MD -1·33, P < 0·001), as did the cosmesis score (short term: MD 3·20, P < 0·001; mid term: MD 4·03, P < 0·001; long-term: MD 4·87, P = 0·05) and the wound satisfaction score (short term: MD 1·19, P = 0·03; mid term: MD 1·38, P < 0·001; long-term: MD 1·19, P = 0·02). Duration of operation was longer for SILC (MD 13·56 min; P < 0·001) and SILC required more additional ports (odds ratio (OR) 6·78; P < 0·001). Postoperative pain assessed by a visual analogue scale (VAS) was lower for SILC at 12 h after operation (MD in VAS score -0·80; P = 0·007). The incisional hernia rate was higher after SILC (OR 2·50, P = 0·03). All other outcomes were similar for both groups.
SILC is associated with better outcomes in terms of cosmesis, body image and postoperative pain. The risk of incisional hernia is four times higher after SILC than after MLC.
本研究旨在评估单切口腹腔镜胆囊切除术(SILC)相较于多孔腹腔镜胆囊切除术(MLC)在美容效果和术后发病率方面的改善情况。
对比较成人良性胆囊疾病患者 SILC 与 MLC 的 RCT 进行了文献检索。主要结局为不同时间点的体像和美容评分。次要结局包括术中及术后并发症、术后疼痛和切口疝的发生频率。
共纳入 37 项 RCT,共计 3051 例患者。体像评分在所有时间点均更倾向 SILC(短期:MD-2.09,P<0.001;中期:MD-1.33,P<0.001),美容评分也是如此(短期:MD3.20,P<0.001;中期:MD4.03,P<0.001;长期:MD4.87,P=0.05),切口满意度评分也是如此(短期:MD1.19,P=0.03;中期:MD1.38,P<0.001;长期:MD1.19,P=0.02)。SILC 的手术时间更长(MD13.56 min;P<0.001),且需要更多附加切口(OR6.78;P<0.001)。术后 12 小时,SILC 的视觉模拟评分(VAS)更低(MD-VAS 评分-0.80;P=0.007)。SILC 后切口疝的发生率更高(OR2.50,P=0.03)。两组其他结局均相似。
SILC 在美容效果、体像和术后疼痛方面的结果更好。SILC 后切口疝的风险比 MLC 高四倍。