Ramakrishnan Deepa, Chidambarathanu Shanthi, Murli Lata, Micheal John, Jagadeesh Sujatha, Suresh Indrani, Seshadri Suresh
a Mediscan Systems , Chennai , India.
Fetal Pediatr Pathol. 2017 Aug;36(4):304-310. doi: 10.1080/15513815.2017.1324546. Epub 2017 Jun 1.
To review fetal autopsy reports with persistent left superior vena cava (PLSVC) and identify its associations.
Autopsy reports of all fetuses diagnosed with PLSVC in our center from January 2011 to December 2015 were reviewed. Fetuses less than 15 weeks gestational age along with autolyzed and damaged hearts were excluded from the study. The study group was compared with controls during this period.
Prenatal ultrasound detection rate of PLSVC was 13.06%. All the cases had associated anomalies of which 96% had extra cardiac anomalies and 67% had intrinsic cardiac defects among which septal defects were most common (39.6%). Anomalies of cardiovascular, respiratory, genitourinary and musculoskeletal, hypoplastic thymus and single umbilical artery were significantly higher in the study group.
This study emphasizes on the importance of improving the technical skill for imaging the three-vessel view as PLSVC seems to have significant associations.
回顾胎儿尸检报告中持续性左上腔静脉（PLSVC）的情况并确定其相关因素。
回顾了2011年1月至2015年12月在本中心诊断为PLSVC的所有胎儿的尸检报告。研究排除了孕龄小于15周以及心脏自溶和受损的胎儿。将研究组与同期的对照组进行比较。
PLSVC的产前超声检出率为13.06%。所有病例均伴有相关畸形，其中96%有心脏外畸形，67%有心脏内在缺陷，其中间隔缺损最为常见（39.6%）。研究组中心血管、呼吸、泌尿生殖和肌肉骨骼、胸腺发育不全及单脐动脉的畸形明显更多。
本研究强调了提高三血管视图成像技术水平的重要性，因为PLSVC似乎有显著的相关因素。
