替加环素治疗广泛耐药鲍曼不动杆菌菌血症婴儿。
Tigecycline treatment in an infant with extensively drug-resistant Acinetobacter baumannii bacteremia.
机构信息
Department of Pharmacy, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
Department of Pediatric Intensive Care Unit, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, 510080, China.
出版信息
Int J Infect Dis. 2017 Aug;61:23-26. doi: 10.1016/j.ijid.2017.05.013. Epub 2017 May 29.
The successful use of tigecycline in a 12-month old liver transplant recipient with extensively drug-resistant Acinetobacter baumannii bacteremia is presented. Tigecycline serum concentrations were monitored to help improve antibiotic efficacy and minimize side effects. A literature review identified 11 additional pediatric cases of A. baumannii infection treated with tigecycline since 2011. Tigecycline treatment should be considered in children with extensively drug-resistant bacterial infections.
本文报告了一例 12 个月大的肝移植受者成功使用替加环素治疗广泛耐药鲍曼不动杆菌菌血症。监测替加环素的血清浓度有助于提高抗生素疗效并减少副作用。文献回顾确定了自 2011 年以来，11 例其他儿童用替加环素治疗的鲍曼不动杆菌感染病例。对于广泛耐药细菌感染的儿童，应考虑使用替加环素治疗。
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