Conway Richard, Orr Carl, McCarthy Geraldine M
Mater Misericordiae University Hospital and CARD Newman Research Fellow, University College Dublin, Dublin, Ireland
Department of Rheumatology, Mater Misericordiae University Hospital, Dublin, Ireland.
Clin Med (Lond). 2017 Jun;17(3):280-281. doi: 10.7861/clinmedicine.17-3-280.
Septic arthritis represents 8-27% of cases of monoarthritis presenting to the emergency department. Tocilizumab is an interleukin-6 blocking monoclonal antibody with the mechanistic potential to interfere with the body's normal inflammatory response to an infectious insult. We present a case of septic arthritis with a normal white cell count, C-reactive protein, erythrocyte sedimentation rate and fibrinogen in a patient treated with tocilizumab.
脓毒性关节炎占急诊科单关节炎病例的8%-27%。托珠单抗是一种白细胞介素-6阻断单克隆抗体,具有干扰机体对感染性损伤正常炎症反应的潜在机制。我们报告了1例接受托珠单抗治疗的患者,其患有脓毒性关节炎,但白细胞计数、C反应蛋白、红细胞沉降率和纤维蛋白原均正常。