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30天再次手术和3个月再入院的危险因素:来自质量与结果数据库腰椎注册登记处的分析

Risk factors for 30-day reoperation and 3-month readmission: analysis from the Quality and Outcomes Database lumbar spine registry.

作者信息

Wadhwa Rishi K, Ohya Junichi, Vogel Todd D, Carreon Leah Y, Asher Anthony L, Knightly John J, Shaffrey Christopher I, Glassman Steven D, Mummaneni Praveen V

机构信息

Department of Neurological Surgery, University of California, San Francisco, California.

Norton Leatherman Spine Center, Louisville, Kentucky.

出版信息

J Neurosurg Spine. 2017 Aug;27(2):131-136. doi: 10.3171/2016.12.SPINE16714. Epub 2017 Jun 2.

Abstract

OBJECTIVE The aim of this paper was to use a prospective, longitudinal, multicenter outcome registry of patients undergoing surgery for lumbar degenerative disease in order to assess the incidence and factors associated with 30-day reoperation and 90-day readmission. METHODS Prospectively collected data from 9853 patients from the Quality and Outcomes Database (QOD; formerly known as the NQOD [National Neurosurgery Quality and Outcomes Database]) lumbar spine registry were retrospectively analyzed. Multivariate binomial regression analysis was performed to identify factors associated with 30-day reoperation and 90-day readmission after surgery for lumbar degenerative disease. A subgroup analysis of Medicare patients stratified by age (< 65 and ≥ 65 years old) was also performed. Continuous variables were compared using unpaired t-tests, and proportions were compared using Fisher's exact test. RESULTS There was a 2% reoperation rate within 30 days. Multivariate analysis revealed prolonged operative time during the index case as the only independent factor associated with 30-day reoperation. Other factors such as preoperative diagnosis, body mass index (BMI), American Society of Anesthesiologists (ASA) class, diabetes, and use of spinal implants were not associated with reoperations within 30 days. Medicare patients < 65 years had a 30-day reoperation rate of 3.7%, whereas those ≥ 65 years had a 30-day reoperation rate of 2.2% (p = 0.026). Medicare beneficiaries younger than 65 years undergoing reoperation within 30 days were more likely to be women (p = 0.009), have a higher BMI (p = 0.008), and have higher rates of depression (p < 0.0001). The 90-day readmission rate was 6.3%. Multivariate analysis demonstrated that higher ASA class (OR 1.46 per class, 95% CI 1.25-1.70) and history of depression (OR 1.27, 95% CI 1.04-1.54) were factors associated with 90-day readmission. Medicare beneficiaries had a higher rate of 90-day readmissions compared with those who had private insurance (OR 1.43, 95% CI 1.17-1.76). Medicare patients < 65 years of age were more likely to be readmitted within 90 days after their index surgery compared with those ≥ 65 years (10.8% vs 7.7%, p = 0.017). Medicare patients < 65 years of age had a significantly higher BMI (p = 0.001) and higher rates of depression (p < 0.0001). CONCLUSIONS In this analysis of a large prospective, multicenter registry of patients undergoing lumbar degenerative surgery, multivariate analysis revealed that prolonged operative time was associated with 30-day reoperation. The authors found that factors associated with 90-day readmission included higher ASA class and a history of depression. The 90-day readmission rates were higher for Medicare beneficiaries than for those who had private insurance. Medicare patients < 65 years of age were more likely to undergo reoperation within 30 days and to be readmitted within 90 days after their index surgery.

摘要

目的 本文旨在利用一个针对接受腰椎退行性疾病手术患者的前瞻性、纵向、多中心结局登记系统,以评估30天再次手术和90天再入院的发生率及相关因素。方法 对前瞻性收集的来自质量与结局数据库(QOD;原名为NQOD[国家神经外科质量与结局数据库])腰椎登记系统的9853例患者的数据进行回顾性分析。进行多变量二项式回归分析,以确定腰椎退行性疾病手术后30天再次手术和90天再入院的相关因素。还对按年龄(<65岁和≥65岁)分层的医疗保险患者进行了亚组分析。连续变量采用不成对t检验进行比较,比例采用Fisher精确检验进行比较。结果 30天内再次手术率为2%。多变量分析显示,初次手术时手术时间延长是与30天再次手术相关的唯一独立因素。其他因素,如术前诊断、体重指数(BMI)、美国麻醉医师协会(ASA)分级、糖尿病和脊柱植入物的使用,与30天内再次手术无关。年龄<65岁的医疗保险患者30天再次手术率为3.7%,而年龄≥65岁的患者30天再次手术率为2.2%(p = 0.026)。年龄<65岁的医疗保险受益患者在30天内接受再次手术的更可能是女性(p = 0.009),BMI更高(p = 0.008),抑郁发生率更高(p < 0.0001)。90天再入院率为6.3%。多变量分析表明,较高的ASA分级(每级OR 1.46,95%CI 1.25 - 1.70)和抑郁病史(OR 1.27,95%CI 1.04 - 1.54)是与90天再入院相关的因素。医疗保险受益患者的90天再入院率高于有私人保险的患者(OR 1.43,95%CI 1.17 - 1.76)。年龄<65岁的医疗保险患者与年龄≥65岁的患者相比,在初次手术后90天内更可能再次入院(10.8%对7.7%,p = 0.017)。年龄<65岁的医疗保险患者BMI显著更高(p = 0.001),抑郁发生率更高(p < 0.0001)。结论 在对接受腰椎退行性手术患者的大型前瞻性、多中心登记系统的本次分析中,多变量分析显示手术时间延长与30天再次手术相关。作者发现与90天再入院相关的因素包括较高的ASA分级和抑郁病史。医疗保险受益患者的90天再入院率高于有私人保险的患者。年龄<65岁的医疗保险患者在初次手术后30天内更可能接受再次手术,在90天内更可能再次入院。

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